The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases
Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger
neurodegeneration through various mechanisms, notably induction of oxidative stress …
neurodegeneration through various mechanisms, notably induction of oxidative stress …
Speciation analysis and fractionation of manganese: A review
E Grygo-Szymanko, A Tobiasz, S Walas - TrAC Trends in Analytical …, 2016 - Elsevier
Manganese as an essential element is required by organisms from simple bacteria to plants,
animals and human beings. The identification and determination of organic or inorganic …
animals and human beings. The identification and determination of organic or inorganic …
Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H‐Ferritin
For more than 150 years, it is known that occupational overexposure of manganese (Mn)
causes movement disorders resembling Parkinson's disease (PD) and PD‐like syndromes …
causes movement disorders resembling Parkinson's disease (PD) and PD‐like syndromes …
Simultaneous quantification and speciation of trace metals in paired serum and CSF samples by size exclusion chromatography–inductively coupled plasma–dynamic …
B Michalke, A Berthele, V Venkataramani - International journal of …, 2021 - mdpi.com
Background: Transition metals play a crucial role in brain metabolism: since they exist in
different oxidation states they are involved in ROS generation, but they are also co-factors of …
different oxidation states they are involved in ROS generation, but they are also co-factors of …
Manganese speciation in paired serum and CSF samples using SEC-DRC-ICP-MS and CE-ICP-DRC-MS
B Michalke, M Lucio, A Berthele, B Kanawati - Analytical and bioanalytical …, 2013 - Springer
Occupational manganese (Mn) overexposure leads to accumulation in the brain and has
been shown to cause progressive, permanent, neuro-degenerative damage with syndromes …
been shown to cause progressive, permanent, neuro-degenerative damage with syndromes …
Separative techniques for metalloproteomics require balance between separation and perturbation
A Hagège, TNS Huynh, M Hébrant - TrAC Trends in Analytical Chemistry, 2015 - Elsevier
Metal-binding proteins play a crucial role in biological systems and associated metals
display many critical functions, so many analytical tools have been developed to identify …
display many critical functions, so many analytical tools have been developed to identify …
An approach for manganese biomonitoring using a manganese carrier switch in serum from transferrin to citrate at slightly elevated manganese concentration
B Michalke, L Aslanoglou… - Journal of Trace …, 2015 - Elsevier
After high-dose-short-term exposure (usually from occupational exposure) and even more
under low-dose long term exposure (mainly environmental) manganese (Mn) biomonitoring …
under low-dose long term exposure (mainly environmental) manganese (Mn) biomonitoring …
Определение химических форм микроэлементов в биологических объектах
НБ Иваненко, НД Соловьев, АА Иваненко… - Аналитика и контроль …, 2012 - elar.urfu.ru
Обобщен опыт определения химических форм микроэлементов в биологических
объектах, основное внимание уделено клиническим объектам анализа. Обсуждены …
объектах, основное внимание уделено клиническим объектам анализа. Обсуждены …
[HTML][HTML] Prolidase activity assays. A survey of the reported literature methodologies
S Fiorito, S Genovese, F Epifano, C Collevecchio - Analytical Biochemistry, 2024 - Elsevier
Abstract Prolidase (EC. 3.4. 13.9) is a dipeptidase known nowadays to play a pivotal role in
several physiological and pathological processes. More in particular, this enzyme is …
several physiological and pathological processes. More in particular, this enzyme is …
Manganese and iron species in Sprague–Dawley rats exposed with MnCl2∙ 4H2O (iv)
J Diederich, M Brielmeier, T Schwerdtle… - Microchemical Journal, 2012 - Elsevier
Chronic manganese exposure leads to accumulation in brain mainly in the basal ganglia.
Continuous incorporation finally causes neural damage (Manganism, Mn-PD) with disease …
Continuous incorporation finally causes neural damage (Manganism, Mn-PD) with disease …