Peripheral coding of taste

ER Liman, YV Zhang, C Montell - Neuron, 2014 - cell.com
Five canonical tastes, bitter, sweet, umami (amino acid), salty, and sour (acid), are detected
by animals as diverse as fruit flies and humans, consistent with a near-universal drive to …

Critical review evaluating the pig as a model for human nutritional physiology

E Roura, SJ Koopmans, JP Lallès… - Nutrition research …, 2016 - cambridge.org
The present review examines the pig as a model for physiological studies in human subjects
related to nutrient sensing, appetite regulation, gut barrier function, intestinal microbiota and …

Taste receptor genes

AA Bachmanov, GK Beauchamp - Annu. Rev. Nutr., 2007 - annualreviews.org
In the past several years, tremendous progress has been achieved with the discovery and
characterization of vertebrate taste receptors from the T1R and T2R families, which are …

The neural mechanisms of gustation: a distributed processing code

SA Simon, IE de Araujo, R Gutierrez… - Nature reviews …, 2006 - nature.com
Whenever food is placed in the mouth, taste receptors are stimulated. Simultaneously,
different types of sensory fibre that monitor several food attributes such as texture …

Genetics of taste receptors

AA Bachmanov, NP Bosak, C Lin… - Current …, 2014 - ingentaconnect.com
Taste receptors function as one of the interfaces between internal and external milieus.
Taste receptors for sweet and umami (T1R [taste receptor, type 1]), bitter (T2R [taste …

Human psychometric and taste receptor responses to steviol glycosides

C Hellfritsch, A Brockhoff, F Stähler… - Journal of agricultural …, 2012 - ACS Publications
Steviol glycosides, the sweet principle of Stevia Rebaudiana (Bertoni) Bertoni, have recently
been approved as a food additive in the EU. The herbal non-nutritive high-potency …

Sweet taste receptor signaling in beta cells mediates fructose-induced potentiation of glucose-stimulated insulin secretion

GA Kyriazis, MM Soundarapandian… - Proceedings of the …, 2012 - pnas.org
Postprandial insulin release is regulated by glucose, but other circulating nutrients may
target beta cells and potentiate glucose-stimulated insulin secretion via distinct signaling …

Sweet and umami taste: natural products, their chemosensory targets, and beyond

M Behrens, W Meyerhof, C Hellfritsch… - Angewandte Chemie …, 2011 - Wiley Online Library
Much of our appreciation of food is due to the excitement of the perception of “sweet” and
“umami” taste. With a special focus on natural products, this Review gives a summary of …

Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds

K Masuda, A Koizumi, K Nakajima, T Tanaka, K Abe… - PloS one, 2012 - journals.plos.org
One of the most distinctive features of human sweet taste perception is its broad tuning to
chemically diverse compounds ranging from low-molecular-weight sweeteners to sweet …

Molecular mechanism of sweetness sensation

GE DuBois - Physiology & behavior, 2016 - Elsevier
The current understanding of peripheral molecular events involved in sweet taste sensation
in humans is reviewed. Included are discussions of the sweetener receptor T1R2/T1R3, its …