[HTML][HTML] Challenges and future trends in the treatment of psoriasis

HJ Lee, M Kim - International journal of molecular sciences, 2023 - mdpi.com
Psoriasis is a chronic inflammatory skin disorder, and current treatments include topical
therapies, phototherapy, systemic immune modulators, and biologics, aiming to alleviate …

IBD matchmaking-rational combination therapy

R Battat, JT Chang, EV Loftus Jr, BE Sands - Clinical Gastroenterology and …, 2024 - Elsevier
A growing number of patients with Crohn's disease and ulcerative colitis have disease that is
refractory to multiple advanced therapies, have undergone multiple surgeries and require …

[HTML][HTML] Phase 3 trials of tapinarof cream for plaque psoriasis

MG Lebwohl, L Stein Gold, B Strober… - … England Journal of …, 2021 - Mass Medical Soc
Background Tapinarof cream is a topical aryl hydrocarbon receptor–modulating agent under
investigation for the treatment of psoriasis. Tapinarof modulates the expression of interleukin …

Effect of roflumilast cream vs vehicle cream on chronic plaque psoriasis: the DERMIS-1 and DERMIS-2 randomized clinical trials

MG Lebwohl, LH Kircik, AY Moore, LS Gold… - Jama, 2022 - jamanetwork.com
Importance Once-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor,
demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis …

[HTML][HTML] One-year safety and efficacy of tapinarof cream for the treatment of plaque psoriasis: Results from the PSOARING 3 trial

B Strober, LS Gold, R Bissonnette… - Journal of the American …, 2022 - Elsevier
Background Tapinarof cream 1% once daily, an aryl hydrocarbon receptor-modulating
agent, was significantly more efficacious than vehicle and well tolerated in two 12-week …

Designing of a new transdermal antibiotic delivery polymeric membrane modified by functionalized SBA-15 mesoporous filler

M Samari, S Kashanian, S Zinadini… - Scientific Reports, 2024 - nature.com
A new drug delivery system using an asymmetric polyethersulfone (PES) membrane
modified by SBA-15 and glutamine-modified SBA-15 (SBA-Q) was prepared in this study by …

Efficacy and safety of curcumin in psoriasis: preclinical and clinical evidence and possible mechanisms

S Zhang, J Wang, L Liu, X Sun, Y Zhou… - Frontiers in …, 2022 - frontiersin.org
Background: Psoriasis is a chronic and immune-mediated inflammatory skin disease. Many
studies have shown that curcumin (CUR) has strong anti-inflammatory effects and can …

Recent approaches for the topical treatment of psoriasis using nanoparticles

K Bodnár, P Fehér, Z Ujhelyi, I Bácskay, L Józsa - Pharmaceutics, 2024 - mdpi.com
Psoriasis (PSO) is a chronic autoimmune skin condition characterized by the rapid and
excessive growth of skin cells, which leads to the formation of thick, red, and scaly patches …

New-onset hidradenitis suppurativa in psoriasis patients: a multi-center, retrospective cohort study

CP Li, SW Lo, RY Tsai, HC Chang, SY Gau - Life, 2024 - mdpi.com
Background: Previous research has indicated a potential correlation between hidradenitis
suppurativa (HS) and psoriasis (PSO), two chronic inflammatory dermatological diseases …

Ameliorative effects of topical ramelteon on imiquimod-induced psoriasiform inflammation in mice

AWM Khafaji, AAK Al-Zubaidy, IG Farhood… - Naunyn-Schmiedeberg's …, 2024 - Springer
Psoriasis is a long-lasting, immune-related inflammatory skin disease that affects 2–3% of
the global population. It is distinguished by erythematous, silvery, and scaly patches …