Pseudomonas aeruginosa Twitching Motility: Type IV Pili in Action

LL Burrows - Annual review of microbiology, 2012 - annualreviews.org
Type IV pili (T4P) are one of the most common forms of bacterial and archaeal surface
structures, involved in adherence, motility, competence for DNA uptake, and pathogenesis …

Type IV pilin proteins: versatile molecular modules

CL Giltner, Y Nguyen, LL Burrows - Microbiology and molecular …, 2012 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a
wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and …

Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions

L Craig, N Volkmann, AS Arvai, ME Pique, M Yeager… - Molecular cell, 2006 - cell.com
Summary Type IV pili (T4P) are long, thin, flexible filaments on bacteria that undergo
assembly-disassembly from inner membrane pilin subunits and exhibit astonishing …

Understanding Pseudomonas aeruginosa–Host Interactions: The Ongoing Quest for an Efficacious Vaccine

M Sainz-Mejías, I Jurado-Martín, S McClean - Cells, 2020 - mdpi.com
Pseudomonas aeruginosa is a leading cause of chronic respiratory infections in people with
cystic fibrosis (CF), bronchiectasis or chronic obstructive pulmonary disease (COPD), and …

Vaccines and immunotherapy against Pseudomonas aeruginosa

G Döring, GB Pier - Vaccine, 2008 - Elsevier
A number of different vaccines and several monoclonal antibodies have been developed in
the last decades for active and passive vaccination against the Gram-negative opportunistic …

The Pseudomonas aeruginosa type IV pilin receptor binding domain functions as an adhesin for both biotic and abiotic surfaces

CL Giltner, EJ Van Schaik, GF Audette… - Molecular …, 2006 - Wiley Online Library
Pseudomonas aeruginosa readily binds to stainless steel and other abiotic surfaces,
causing major problems in both the medical and food industries. In this study, we show that …

DNA Binding: a Novel Function of Pseudomonas aeruginosa Type IV Pili

EJ Van Schaik, CL Giltner, GF Audette… - Journal of …, 2005 - Am Soc Microbiol
The opportunistic pathogen Pseudomonas aeruginosa produces multifunctional, polar,
filamentous appendages termed type IV pili. Type IV pili are involved in colonization during …

Recent developments for Pseudomonas vaccines

A Sharma, A Krause, S Worgall - Human vaccines, 2011 - Taylor & Francis
Infections with Pseudomonas aeruginosa are a major health problem for immune-
compromised patients and individuals with cystic fibrosis. A vaccine against P. aeruginosa …

Intervention with bacterial adhesion by multivalent carbohydrates

RJ Pieters - Medicinal research reviews, 2007 - Wiley Online Library
Bacterial adhesion is often a prelude to infection. In many cases, this process is governed by
protein–carbohydrate interactions. Intervention at this early stage of infection is a …

Structural diversity in the type IV pili of multidrug-resistant Acinetobacter

KH Piepenbrink, E Lillehoj, CM Harding… - Journal of Biological …, 2016 - ASBMB
Acinetobacter baumannii is a Gram-negative coccobacillus found primarily in hospital
settings that has recently emerged as a source of hospital-acquired infections. A. baumannii …