Research in computer analysis of medical images bears many promises to improve patients'
health. However, a number of systematic challenges are slowing down the progress of the …

Sustainable development is a key challenge for contemporary human societies; failure to
achieve sustainability could threaten human survival. In this review article, we illustrate how …

Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …

Scientists often adjust their significance threshold (alpha level) during null hypothesis
significance testing in order to take into account multiple testing and multiple comparisons …

We evaluated 1038 of the most cited structural and functional (fMRI) magnetic resonance
brain imaging papers (1161 studies) published during 1990–2012 and 270 papers (300 …

A fundamental goal across the neurosciences is the characterization of relationships linking
brain anatomy, functioning, and behavior. Although various MRI modalities have been …

Abstract Analysis of secondary data sources (such as cohort studies, survey data, and
administrative records) has the potential to provide answers to science and society's most …

After a natural experiment is first used, other researchers often reuse the setting, examining
different outcome variables. We use simulations based on real data to illustrate the multiple …

Psychological science is on an extraordinary winning streak. A review of the published
literature shows that nearly all study hypotheses are supported. This means that either all …

Large, open datasets have emerged as important resources in the field of human
connectomics. In this review, the evolution of data sharing involving magnetic resonance …