Antimicrobial metabolites of Caucasian medicinal plants as alternatives to antibiotics

M Fik-Jaskółka, V Mittova, C Motsonelidze, M Vakhania… - Antibiotics, 2024 - mdpi.com
This review explores the potential of antimicrobial metabolites derived from Caucasian
medicinal plants as alternatives to conventional antibiotics. With the rise of antibiotic …

Call for next-generation drugs that remove the uptake barrier to combat antibiotic resistance

B Peng, H Li, X Peng - Drug Discovery Today, 2023 - Elsevier
Highlights•Next-generation antibacterial agents are urgently needed to combat multidrug-
resistant, pandrug-resistant gram-negative bacteria and superbugs.•Next generation …

Efflux pump inhibitors in controlling antibiotic resistance: outlook under a heavy metal contamination context

THT Nguyen, HD Nguyen, MH Le, TTH Nguyen… - Molecules, 2023 - mdpi.com
Multi-drug resistance to antibiotics represents a growing challenge in treating infectious
diseases. Outside the hospital, bacteria with the multi-drug resistance (MDR) phenotype …

[HTML][HTML] Methods for Determination of Antimicrobial Activity of Essential Oils In Vitro—A Review

R Hulankova - Plants, 2024 - mdpi.com
Essential oils (EOs) have been gaining popularity in the past decades among researchers
due to their potential to replace conventional chemicals used in the fight against pests …

[HTML][HTML] The recent progress of tricyclic aromadendrene-type sesquiterpenoids: Biological activities and biosynthesis

X Yan, J Lin, Z Liu, SD David, D Liang, S Nie, M Ge… - Biomolecules, 2024 - mdpi.com
The tricyclic-aromadendrene-type sesquiterpenes are widely distributed and exhibit a range
of biological activities, including anti-inflammatory, analgesic, antioxidant, antibacterial …

[HTML][HTML] Valencene, nootkatone and their liposomal nanoformulations as potential inhibitors of NorA, Tet (K), MsrA, and MepA efflux pumps in Staphylococcus aureus …

CDM Oliveira-Tintino, JEG Santana, GG Alencar… - Pharmaceutics, 2023 - mdpi.com
Valencene and nootkatone are aromatic sesquiterpenes with known biological activities,
such as antimicrobial, antioxidant, anti-inflammatory, and antitumor. Given the evidence that …

Hoslundia opposita vahl; a potential source of bioactive compounds with antioxidant and antibiofilm activity for wound healing

C Namuga, H Muwonge, K Nasifu, P Sekandi… - … Medicine and Therapies, 2024 - Springer
Background Biofilms and oxidative stress retard wound healing. The resistance of biofilms to
antibiotics has led to a search for alternative approaches in biofilm elimination. Antioxidants …

[HTML][HTML] Repositioning of HMG-CoA reductase inhibitors as adjuvants in the modulation of efflux pump-mediated bacterial and tumor resistance

Z Schelz, HF Muddather, I Zupkó - Antibiotics, 2023 - mdpi.com
Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial
infections and neoplastic diseases. The diversity and lack of specificity of these efflux …

[HTML][HTML] Essential oil compounds in combination with conventional antibiotics for dermatology

S Simbu, A Orchard, S Vuuren - Molecules, 2024 - mdpi.com
Antimicrobial resistance has emerged as a significant threat to public health, prompting
novel combinations comprising of natural sources such as essential oil compounds with …

Assessment of antibacterial, antioxidant, cytotoxic properties and chemical composition of Oenanthe javanica (Blume) DC. essential oil

R Kumar, P Singh - Journal of Herbal Medicine, 2025 - Elsevier
Introduction Bacterial food-borne diseases have been a major public health issue worldwide
for decades. Oenanthe javanica (Blume) DC. is a small perennial herb of family Apiaceae …