Clear cell carcinoma of the ovary is a rare and distinct histotype of epithelial ovarian
carcinomas. Women diagnosed with clear cell carcinomas are usually younger and …

Ovarian cancer (OC) is one of the most common malignant tumors in women. OC is
associated with the activation of oncogenes, the inactivation of tumor suppressor genes, and …

Abstract Cancer-associated, loss-of-function mutations in genes encoding subunits of the
BRG1/BRM-associated factor (BAF) chromatin-remodeling complexes,,,,,,–often cause …

Using genome-wide clustered regularly interspaced short palindromic repeats (CRISPR)
screens to understand endocrine drug resistance, we discovered ARID1A and other …

Liquid-liquid phase separation (LLPS) facilitates the formation of membraneless organelles
within cells, with implications in various biological processes and disease states. AT-rich …

Low‐grade serous ovarian carcinoma (LGSOC) is associated with a poor response to
existing chemotherapy, highlighting the need to perform comprehensive genomic analysis …

NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene.
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …

Endometriosis is a benign gynecologic condition affecting up to one woman out of ten of
reproductive age. It is defined by the presence of endometrial-like tissue in localizations …

Ovarian cancer is one of the deadliest cancers in women. The lack of specific symptoms,
especially at the initial stages of disease development, together with the malignancy …

Abstract AT-Rich Interaction Domain 1A (ARID1A) is an important SWItch/Sucrose Non-
Fermentation (SWI/SNF) chromatin remodeling complex subunit, and its coding gene has a …