Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments

AI Pérez-Jiménez, D Lyu, Z Lu, G Liu, B Ren - Chemical science, 2020 - pubs.rsc.org
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique
with sensitivity down to the single molecule level that provides fine molecular fingerprints …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Functional DNA regulated CRISPR-Cas12a sensors for point-of-care diagnostics of non-nucleic-acid targets

Y **ong, J Zhang, Z Yang, Q Mou, Y Ma… - Journal of the …, 2019 - ACS Publications
Beyond its extraordinary genome editing ability, the CRISPR-Cas systems have opened a
new era of biosensing applications due to its high base resolution and isothermal signal …

Metal-organic frameworks for stimuli-responsive drug delivery

Y Wang, J Yan, N Wen, H **ong, S Cai, Q He, Y Hu… - Biomaterials, 2020 - Elsevier
Abstract Metal-organic framework (MOF), a novel hybrid porous material which is
composited by metal ions and organic linkers, has drawn increasing attention and became a …

Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development

H Yu, O Alkhamis, J Canoura, Y Liu… - Angewandte Chemie …, 2021 - Wiley Online Library
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Electrically-transduced chemical sensors based on two-dimensional nanomaterials

Z Meng, RM Stolz, L Mendecki, KA Mirica - Chemical reviews, 2019 - ACS Publications
Electrically–transduced sensors, with their simplicity and compatibility with standard
electronic technologies, produce signals that can be efficiently acquired, processed, stored …

Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts

MP Stewart, R Langer, KF Jensen - Chemical reviews, 2018 - ACS Publications
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Metal sensing by DNA

W Zhou, R Saran, J Liu - Chemical reviews, 2017 - ACS Publications
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …