Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - Am Heart Assoc
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Angiogenesis in life, disease and medicine

P Carmeliet - Nature, 2005 - nature.com
The growth of blood vessels (a process known as angiogenesis) is essential for organ
growth and repair. An imbalance in this process contributes to numerous malignant …

What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

JM Wardlaw, MC Valdés Hernández… - Journal of the …, 2015 - Am Heart Assoc
White matter hyperintensities (WMH) of presumed vascular origin, also referred to as
leukoaraiosis, are a very common finding on brain magnetic resonance imaging (MRI) or …

National Institute of Neurological Disorders and Stroke–Canadian stroke network vascular cognitive impairment harmonization standards

V Hachinski, C Iadecola, RC Petersen, MM Breteler… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—One in 3 individuals will experience a stroke, dementia or both.
Moreover, twice as many individuals will have cognitive impairment short of dementia as …

[HTML][HTML] Stroke injury, cognitive impairment and vascular dementia

RN Kalaria, R Akinyemi, M Ihara - … Acta (BBA)-Molecular Basis of Disease, 2016 - Elsevier
The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes.
Current evidence suggests that 25–30% of ischaemic stroke survivors develop immediate or …

The overlap between vascular disease and Alzheimer's disease-lessons from pathology

J Attems, KA Jellinger - BMC medicine, 2014 - Springer
Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement

P Sachdev, R Kalaria, J O'Brien, I Skoog… - Alzheimer Disease & …, 2014 - journals.lww.com
Background: Several sets of diagnostic criteria have been published for vascular dementia
since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical …

A clinicopathological approach to the diagnosis of dementia

FM Elahi, BL Miller - Nature Reviews Neurology, 2017 - nature.com
The most definitive classification systems for dementia are based on the underlying
pathology which, in turn, is categorized largely according to the observed accumulation of …

The pathology and pathophysiology of vascular dementia

RN Kalaria - Neuropharmacology, 2018 - Elsevier
Vascular dementia (VaD) is widely recognised as the second most common type of
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease

RN Kalaria - Acta neuropathologica, 2016 - Springer
Vascular dementia (VaD) is recognised as a neurocognitive disorder, which is explained by
numerous vascular causes in the general absence of other pathologies. The heterogeneity …