HFIP in organic synthesis

HF Motiwala, AM Armaly, JG Cacioppo… - Chemical …, 2022 - ACS Publications
1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Photochemical and electrochemical applications of proton-coupled electron transfer in organic synthesis

PRD Murray, JH Cox, ND Chiappini, CB Roos… - Chemical …, 2021 - ACS Publications
We present here a review of the photochemical and electrochemical applications of multi-
site proton-coupled electron transfer (MS-PCET) in organic synthesis. MS-PCETs are redox …

Cross-dehydrogenative coupling: a sustainable reaction for C–C bond formations

T Tian, Z Li, CJ Li - Green Chemistry, 2021 - pubs.rsc.org
We are entering an era that emphasizes greenness and sustainability. Based on such a
philosophy, it is critical to uncover novel and original sustainable reaction modes for future …

Recent Advances in Oxidative R1-H/R2-H Cross-Coupling with Hydrogen Evolution via Photo-/Electrochemistry: Focus Review

H Wang, X Gao, Z Lv, T Abdelilah, A Lei - Chemical reviews, 2019 - ACS Publications
Photo-/electrochemical catalyzed oxidative R1-H/R2-H cross-coupling with hydrogen
evolution has become an increasingly important issue for molecular synthesis. The dream of …

Electrochemical strategies for C–H functionalization and C–N bond formation

MD Kärkäs - Chemical Society Reviews, 2018 - pubs.rsc.org
Conventional methods for carrying out carbon–hydrogen functionalization and carbon–
nitrogen bond formation are typically conducted at elevated temperatures, and rely on …

Synthetic organic electrochemical methods since 2000: on the verge of a renaissance

M Yan, Y Kawamata, PS Baran - Chemical Reviews, 2017 - ACS Publications
Electrochemistry represents one of the most intimate ways of interacting with molecules. This
review discusses advances in synthetic organic electrochemistry since 2000. Enabling …

A decade of electrochemical dehydrogenative C, C-coupling of aryls

JL Röckl, D Pollok, R Franke… - Accounts of Chemical …, 2019 - ACS Publications
Conspectus The importance of sustainable and green synthetic protocols for the synthesis of
fine chemicals has rapidly increased during the last decades in an effort to reduce the use of …

Electrifying organic synthesis

A Wiebe, T Gieshoff, S Möhle, E Rodrigo… - Angewandte Chemie …, 2018 - Wiley Online Library
The direct synthetic organic use of electricity is currently experiencing a renaissance. More
synthetically oriented laboratories working in this area are exploiting both novel and more …

Electrochemical arylation reaction

SR Waldvogel, S Lips, M Selt, B Riehl… - Chemical …, 2018 - ACS Publications
Arylated products are found in various fields of chemistry and represent essential entities for
many applications. Therefore, the formation of this structural feature represents a central …

Electrocatalytic C–H Activation

N Sauermann, TH Meyer, Y Qiu, L Ackermann - Acs Catalysis, 2018 - ACS Publications
C–H activation has emerged as a transformative tool in molecular synthesis, but until
recently oxidative C–H activations have largely involved the use of stoichiometric amounts of …