The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

[HTML][HTML] Oxytocin in general anxiety and social fear: a translational approach

ID Neumann, DA Slattery - Biological psychiatry, 2016 - Elsevier
The neuropeptide oxytocin (OXT) has been revealed as a profound anxiolytic and antistress
factor of the brain, besides its many prosocial and reproductive effects. Therefore, there is …

[HTML][HTML] MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms?

AA Feduccia, MC Mithoefer - Progress in neuro-psychopharmacology and …, 2018 - Elsevier
MDMA-assisted psychotherapy for treatment of PTSD has recently progressed to Phase 3
clinical trials and received Breakthrough Therapy designation by the FDA. MDMA used as …

Kinetics and dose dependency of intranasal oxytocin effects on amygdala reactivity

FB Spengler, J Schultz, D Scheele, M Essel, W Maier… - Biological …, 2017 - Elsevier
Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits

DA Baribeau, E Anagnostou - Frontiers in neuroscience, 2015 - frontiersin.org
Oxytocin and vasopressin are pituitary neuropeptides that have been shown to affect social
processes in mammals. There is growing interest in these molecules and their receptors as …

Oxytocin and the neurobiology of prosocial behavior

N Marsh, AA Marsh, MR Lee… - The …, 2021 - journals.sagepub.com
Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

Calming effects of touch in human, animal, and robotic interaction—scientific state-of-the-art and technical advances

M Eckstein, I Mamaev, B Ditzen, U Sailer - Frontiers in psychiatry, 2020 - frontiersin.org
Small everyday gestures such as a tap on the shoulder can affect the way humans feel and
act. Touch can have a calming effect and alter the way stress is handled, thereby promoting …

Sex differences in fear extinction

ER Velasco, A Florido, MR Milad, R Andero - … & Biobehavioral Reviews, 2019 - Elsevier
Despite the exponential increase in fear research during the last years, few studies have
included female subjects in their design. The need to include females arises from the …