Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …

Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent disease and important unmet
medical need. Current guidelines recommend, under specific restrictions, pioglitazone or …

Inflammatory disease (ID) is an umbrella term encompassing all illnesses involving chronic
inflammation as the central manifestation of pathogenesis. These include, inflammatory …

Spinal cord injury (SCI) is an irreversible disease process with a high disability and mortality
rate. After primary spinal cord injury, the secondary injury may occur in sequence, which is …

Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …

Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-dysfunction-
associated fatty liver disease (MAFLD), affects a quarter of the worldwide population. Natural …

Over almost 140 years since their identification, the knowledge about macrophages has
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …

Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …

Autoimmune diseases resulting from MHC class II–restricted autoantigen-specific T cell
immunity include the systemic inflammatory autoimmune conditions rheumatoid arthritis and …