The axon is a neuronal structure capable of processing, encoding, and transmitting
information. This assessment contrasts with a limiting, but deeply rooted, perspective where …

Retinoic acid (RA), the derivative of vitamin A/retinol, is a signaling molecule with important
implications in health and disease. It is a well-known developmental morphogen that …

Homeostatic plasticity of intrinsic excitability goes hand in hand with homeostatic plasticity of
synaptic transmission. However, the mechanisms linking the two forms of homeostatic …

Excitable cells of the nervous and cardiovascular systems depend on an assortment of
plasmalemmal potassium channels to control diverse cellular functions. Voltage-gated …

The study of metabolism is undergoing a renaissance. Since the year 2002, over 50
genetically-encoded fluorescent indicators (GEFIs) have been introduced, capable of …

Rapid and precise neuronal communication is enabled through a highly synchronous
release of signaling molecules neurotransmitters within just milliseconds of the action …

All‐or‐none signalling by action potentials (APs) in neuronal axons is pivotal for the
precisely timed and identical size of outputs to multiple distant targets. However, technical …

The immediate early gene FOS is frequently used as a marker for highly active neurons.
Implicit in this use is the assumption that there is a correlation between neuronal spiking and …

The initiation and propagation of the action potential (AP) along an axon allows neurons to
convey information rapidly and across distant sites. Although AP properties have typically …

Two KCNA2 variants (p. H310Y and p. H310R) were discovered in paediatric patients with
epilepsy and developmental delay. KCNA2 encodes KV1. 2‐channel subunits, which …