Biology of melanoma
SM Ostrowski, DE Fisher - Hematology/Oncology Clinics, 2021 - hemonc.theclinics.com
Melanoma skin cancer is derived from skin melanocytes and has a high risk of metastatic
spread. Many clinical attributes and risk factors associated with melanoma have been well …
spread. Many clinical attributes and risk factors associated with melanoma have been well …
Sun exposure and skin cancer, and the puzzle of cutaneous melanoma: a perspective on Fears et al. Mathematical models of age and ultraviolet effects on the …
BK Armstrong, AE Cust - Cancer epidemiology, 2017 - Elsevier
Sunlight has been known as an important cause of skin cancer since around the turn of the
20th Century. A 1977 landmark paper of US scientists Fears, Scotto, and Schneiderman …
20th Century. A 1977 landmark paper of US scientists Fears, Scotto, and Schneiderman …
[HTML][HTML] MC1R signaling. Intracellular partners and pathophysiological implications
C Herraiz, JC Garcia-Borron… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract The melanocortin-1 receptor (MC1R) preferentially expressed in melanocytes is
best known as a key regulator of the synthesis of epidermal melanin pigments. Its paracrine …
best known as a key regulator of the synthesis of epidermal melanin pigments. Its paracrine …
A review of nevus‐associated melanoma: What is the evidence?
C Dessinioti, AC Geller… - Journal of the European …, 2022 - Wiley Online Library
Cutaneous melanoma may have an adjacent nevus remnant on histological examination in
30% of cases (nevus‐associated melanoma, NAM), while it may appear de novo, without a …
30% of cases (nevus‐associated melanoma, NAM), while it may appear de novo, without a …
Behind the scene: exploiting MC1R in skin cancer risk and prevention
Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the
skin in white populations. An increased risk in the development of skin cancers has been …
skin in white populations. An increased risk in the development of skin cancers has been …
Systemic BRAF/MEK inhibitors as a potential treatment option in metastatic conjunctival melanoma
JM Mor, LM Heindl - Ocular Oncology and Pathology, 2017 - karger.com
Aim: In this review, we outline similarities between conjunctival and skin melanoma as well
as the effectiveness of combined BRAF/MEK inhibition in melanoma, and discuss the …
as the effectiveness of combined BRAF/MEK inhibition in melanoma, and discuss the …
Melanoma–role of the environment and genetics
Melanoma rates have increased in populations that are mainly European. The main
etiologic factor is ultraviolet radiation, from the sun as well as artificial tanning devices. Host …
etiologic factor is ultraviolet radiation, from the sun as well as artificial tanning devices. Host …
[HTML][HTML] Factors related to nevus-associated cutaneous melanoma: a case-case study
A proportion of cutaneous melanomas display neval remnants on histologic examination.
Converging lines of epidemiologic and molecular evidence suggest that melanomas arising …
Converging lines of epidemiologic and molecular evidence suggest that melanomas arising …
PRAME Is an Effective Tool for the Diagnosis of Nevus-Associated Cutaneous Melanoma
Simple Summary Nevus-associated cutaneous melanoma (CM) is a malignant melanocytic
proliferation occurring in the context of a pre-existing benign melanocytic nevus. This type of …
proliferation occurring in the context of a pre-existing benign melanocytic nevus. This type of …
The association between BRAF‐V600E mutations and death from thin (≤ 1.00 mm) melanomas: A nested case–case study from Queensland, Australia
M Claeson, SX Tan, D Lambie, S Brown… - Journal of the …, 2023 - Wiley Online Library
Dear Editor, In the state of Queensland, Australia, 68% of invasive cutaneous melanomas
are diagnosed at a thin (≤ 1.00 mm) stage and have high survival rates (> 95%). 1, 2 …
are diagnosed at a thin (≤ 1.00 mm) stage and have high survival rates (> 95%). 1, 2 …