The impacts of glucocorticoids (GCs) are mainly mediated by a nuclear receptor (GR)
existing in almost every tissue. The GR regulates a wide range of physiological functions …

Sepsis is an acute systemic inflammatory disease. Glucocorticoids (GCs), which function by
binding to the GC receptor GR have very powerful anti-inflammatory activities, yet they are …

Introduction: Myasthenia gravis (MG) is an autoimmune neuromuscular disorder with no
cure and conventional treatments limited by significant adverse effects and variable benefit …

Chronic, high-dose, oral prednisone has been the mainstay of myasthenia gravis treatment
for decades and has proven to be highly beneficial in many, toxic in some way to all, and not …

The presence of autoantibodies directed against the muscle nicotinic acetylcholine receptor
(AChR) is the most common cause of myasthenia gravis (MG). These antibodies damage …

Myasthenia gravis (MG) stands as a prototypical antibody-mediated autoimmune disease: it
is dependent on T cells and characterized by the presence of autoantibodies targeting …

Objective To understand the current situation of job burnout among coal miners in **njian.
The effects of occupational stress, GCCR and SLC6A4 gene polymorphisms, and gene …

Objective High-dose prednisone use, lasting several months or longer, is the primary initial
therapy for myasthenia gravis (MG). Upwards of a third of patients do not respond to …

Glomerular diseases (GNs) are responsible for approximately 20% of chronic kidney
diseases. Glucocorticoid receptor gene (NR3C1) single nucleotide polymorphisms (SNPs) …

Background Ocular myasthenia gravis (OMG) is an autoimmune disease which causes
ptosis, diplopia, or both. It can be categorized as early or late onset, with differing presenting …