Plasmalogens (1-O-alk-1′-enyl-2-acyl glycerophospholipids) constitute a special class of
phospholipids characterized by the presence of a vinyl–ether bond at the sn-1 position …

Glycolysis is perceived as a promising target for new drugs against parasitic trypanosomatid
protozoa because this pathway plays an essential role in their ATP supply. Trypanosomatid …

Kinetoplastida are protozoan organisms that probably diverged early in evolution from other
eukaryotes. They are characterized by a number of unique features with respect to their …

Trypanosomatid parasites cause serious diseases among humans, livestock, and plants.
They belong to the order of the Kinetoplastida and form, together with the Euglenida, the …

In recent years, much progress has been made with respect to the unravelling of the
functions of peroxisomes in metabolism, and it is now well established that peroxisomes are …

In all trypanosomatids, includingTrypanosoma brucei, glycolysis takes place in peroxisome-
like organelles called glycosomes. These are closed compartments wherein the energy and …

Peroxisomes are present in nearly every eukaryotic cell and compartmentalize a wide range
of important metabolic processes. Glycosomes of Kinetoplastid parasites are peroxisome …

We present the molecular karyotype of the megabase chromosomes of Trypanosoma brucei
stock 427, clone 221a. This cloned stock is most commonly used in research laboratories in …

Subspecies of the African trypanosome, Trypanosoma brucei, which cause human African
trypanosomiasis, are transmitted by the tsetse fly, with transmission‐essential lifecycle …

Abstract Background: NAD-dependent glycerol-3-phosphate dehydrogenase (GPDH)
catalyzes the interconversion of dihydroxyacetone phosphate and l-glycerol-3-phosphate …