Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral
hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a …

Simple Summary The new trends in the research on glioblastomas (GBMs) are focusing on
understanding the crosstalk between proper neoplastic tissue and its microenvironment …

Cancer remains a serious burden in society and while the pace in the development of novel
and more effective therapeutics is increasing, testing platforms that faithfully mimic the tumor …

Glioblastoma (GBM) is the most common intrinsic and aggressive primary brain tumor in
adults, with a median survival of approximately 15 months. GBM heterogeneity is considered …

High-grade adult-type diffuse gliomas are the most common and deadliest malignant adult
tumors of the central nervous system. Despite the advancements in the multimodality …

Epidemiological studies have shown that the consumption of green tea has beneficial effects
against cancer. Basic studies have provided evidence that epigallocatechin gallate (EGCG) …

Previous studies have shown that tumors under a hypoxic environment can induce an
important hypoxia-responsive element, hypoxia-induced factor-1α (HIF-1α), which can …

Background: Triple-negative breast cancer (TNBC) cells secretome induces a pro-
inflammatory microenvironment within the adipose tissue, which hosts both mature …

Despite advancements in chemotherapy, the issue of resistance and non-responsiveness to
many chemotherapeutic drugs that are currently in clinical use still remains. Recently …

Immunomodulatory therapies, including immune checkpoint inhibitors, have drastically
changed outcomes for certain cancer types over the last decade. Gliomas are among the …