Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

Gut microbiota and complications of type-2 diabetes

CO Iatcu, A Steen, M Covasa - Nutrients, 2021 - mdpi.com
The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …

NAFLD as a driver of chronic kidney disease

CD Byrne, G Targher - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Type 2 diabetes mellitus-associated cognitive dysfunction: advances in potential mechanisms and therapies

A Luo, Z **e, Y Wang, X Wang, S Li, J Yan… - Neuroscience & …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) and its target organ injuries cause distressing impacts on
personal health and put an enormous burden on the healthcare system, and increasing …

Dysbiosis of Gram-negative gut microbiota and the associated serum lipopolysaccharide exacerbates inflammation in type 2 diabetic patients with chronic kidney …

MV Salguero, MAI Al-Obaide… - Experimental and …, 2019 - spandidos-publications.com
Lipopolysaccharide (LPS), a potent endotoxin present in the outer membrane of Gram-
negative bacteria, causes chronic immune responses associated with inflammation. In the …

Alterations to the gut microbiota and their correlation with inflammatory factors in chronic kidney disease

FX Li, MH Wang, JP Wang, RS Li… - Frontiers in Cellular and …, 2019 - frontiersin.org
Alterations to the gut microbiota have been previously suggested to be tightly linked to
chronic systemic inflammation, which is a major contributing factor to complications and …

Role of gut microbiota on onset and progression of microvascular complications of type 2 diabetes (T2DM)

DM Tanase, EM Gosav, E Neculae, CF Costea… - Nutrients, 2020 - mdpi.com
Type 2 diabetes mellitus (T2DM) remains one of the most problematic and economic
consumer disorders worldwide, with growing prevalence and incidence. Over the last years …

Resveratrol modulates the gut microbiota and inflammation to protect against diabetic nephropathy in mice

TT Cai, XL Ye, RR Li, H Chen, YY Wang… - Frontiers in …, 2020 - frontiersin.org
Oral administration of resveratrol is able to ameliorate the progression of diabetic
nephropathy (DN); however, its mechanisms of action remain unclear. Recent evidence …

Probiotics improve renal function, glucose, lipids, inflammation and oxidative stress in diabetic kidney disease: a systematic review and meta-analysis

Y Dai, J Quan, L **ong, Y Luo, B Yi - Renal failure, 2022 - Taylor & Francis
Aims The role of probiotics in the management of diabetic kidney disease (DKD) has been
shown. Several current trials are investigating the effect of probiotics, which are widely used …

Causal Relationship between Diet-Induced Gut Microbiota Changes and Diabetes: A Novel Strategy to Transplant Faecalibacterium prausnitzii in Preventing …

K Ganesan, SK Chung, J Vanamala, B Xu - International journal of …, 2018 - mdpi.com
The incidence of metabolic disorders, including diabetes, has elevated exponentially during
the last decades and enhanced the risk of a variety of complications, such as diabetes and …