Lentiviral vectors as a vaccine platform against infectious diseases

K Nemirov, M Bourgine, F Anna, Y Wei, P Charneau… - Pharmaceutics, 2023 - mdpi.com
Lentiviral vectors are among the most effective viral vectors for vaccination. In clear contrast
to the reference adenoviral vectors, lentiviral vectors have a high potential for transducing …

The impact of oral health on respiratory viral infection

A Tada, H Senpuku - Dentistry Journal, 2021 - mdpi.com
Influenza virus and severe acute respiratory syndrome coronavirus (SARS-CoV-2) have
caused respiratory diseases worldwide. Coronavirus disease 2019 (COVID-19) is now a …

Streptococcus pneumoniae colonization associates with impaired adaptive immune responses against SARS-CoV-2

E Mitsi, J Reiné, BC Urban, C Solórzano… - The Journal of …, 2022 - Am Soc Clin Investig
Background Although recent epidemiological data suggest that pneumococci may contribute
to the risk of SARS-CoV-2 disease, cases of coinfection with Streptococcus pneumoniae in …

Electronic-cigarette use alters nasal mucosal immune response to live-attenuated influenza virus. A clinical trial

ME Rebuli, E Glista-Baker, JR Hoffman… - American journal of …, 2021 - atsjournals.org
Inhalation of tobacco smoke has been linked to increased risk of viral infection, such as
influenza. Inhalation of electronic-cigarette (e-cigarette) aerosol has also recently been …

Two MP2CL5 antigen vaccines from Naegleria fowleri stimulate the immune response against meningitis in the BALB/c model

M Gutiérrez-Sánchez, MM Carrasco-Yépez… - Infection and …, 2023 - Am Soc Microbiol
Naegleria fowleri is an etiological agent that generates primary amoebic
meningoencephalitis; unfortunately, no effective treatment or vaccine is available. The …

Intranasal M2SR (M2-deficient single replication) H3N2 influenza vaccine provides enhanced mucosal and serum antibodies in adults

J Eiden, C Fierro, H Schwartz, M Adams… - The Journal of …, 2023 - academic.oup.com
Background We previously demonstrated that an intranasal dose of 108 50% tissue culture
infectious dose (TCID50) M2-deficient single replication (M2SR) influenza vaccine protected …

SARS-CoV-2 specific sIgA in saliva increases after disease-related video stimulation

JK Keller, A Dulovic, J Gruber, J Griesbaum… - Scientific Reports, 2023 - nature.com
Secretory immunoglobulin A (sIgA) in saliva is the most important immunoglobulin fighting
pathogens in the respiratory tract and may thus play a role in preventing SARS-CoV-2 …

The potential of neuraminidase as an antigen for nasal vaccines to increase cross-protection against influenza viruses

A Kawai, Y Yamamoto, T Nogimori, K Takeshita… - Journal of …, 2021 - Am Soc Microbiol
Despite the availability of vaccines that efficiently reduce the severity of clinical symptoms,
influenza viruses still cause substantial morbidity and mortality worldwide. In this regard …

Factors influencing the immunogenicity of influenza vaccines

S Wen, Z Wu, S Zhong, M Li, Y Shu - Human vaccines & …, 2021 - Taylor & Francis
Annual vaccination is the best prevention of influenza. However, the immunogenicity of
influenza vaccines varies among different populations. It is important to fully identify the …

Double-layered protein nanoparticles conjugated with truncated flagellin induce improved mucosal and systemic immune responses in mice

JK Kim, W Zhu, C Dong, L Wei, Y Ma, T Denning… - Nanoscale …, 2024 - pubs.rsc.org
Influenza viral infection poses a severe risk to global public health. Considering the
suboptimal protection provided by current influenza vaccines against circulating influenza A …