Brain-derived neurotrophic factor (BDNF) and its downstream tropomyosin receptor kinase B
(TrkB) signaling pathway play pivotal roles in the resilience and action of antidepressant …

Neuroinflammation in response to environmental stressors is an important common pathway
in a number of neurological and psychiatric disorders. Responses to immune-mediated …

Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by
beta-amyloid (Aβ) deposition and increased acetylcholinesterase (AchE) enzyme activities …

Ischemic stroke is a devastating disease that causes morbidity and mortality. Malnutrition
following ischemic stroke is common in stroke patients. During the rehabilitation, the death …

Stroke is a serious condition often resulting in mortality or long-term disability, causing
cognitive, memory, and motor impairments. A reduction in cerebral blood flow below critical …

Oxidative stress is a common feature of neurodegenerative diseases. Different natural
compounds mediate neuroprotective effects by activating the Nrf2 antioxidant response …

Background Alzheimer's disease (AD) is a neurodegenerative disease that leads to
development of cognition and memory dysfunctions. Currently, there is no known cure for …

Prolonged exposure to glucocorticoids (GC) disrupts neuronal architecture, hinders
neuroplasticity, and triggers neuroinflammation. However, the precise underlying …

While studies of nutritional factors in non-human models of HD have shown some promising
results, trials in humans have found little efficacy for diets or supplements. The complexity of …

Global cerebral ischemia (GCI) is associated with a multifaceted etiology, including
increased oxidative stress, inflammation, and elevated acetylcholinesterase (AChE) activity …