Climate change in the North American Arctic: A one health perspective

JP Dudley, EP Hoberg, EJ Jenkins, AJ Parkinson - EcoHealth, 2015‏ - Springer
Climate change is expected to increase the prevalence of acute and chronic diseases
among human and animal populations within the Arctic and subarctic latitudes of North …

Marked for life: epigenetic effects of endocrine disrupting chemicals

MN Jacobs, EL Marczylo… - Annual Review of …, 2017‏ - annualreviews.org
The presence of human-made chemical contaminants in the environment has increased
rapidly during the past 70 years. Harmful effects of such contaminants were first reported in …

Forecasting the relative influence of environmental and anthropogenic stressors on polar bears

TC Atwood, BG Marcot, DC Douglas, SC Amstrup… - …, 2016‏ - Wiley Online Library
Effective conservation planning requires understanding and ranking threats to wildlife
populations. We developed a Bayesian network model to evaluate the relative influence of …

Interactions of perfluoroalkyl substances with a phospholipid bilayer studied by neutron reflectometry

S Nouhi, L Ahrens, HC Pereira, AV Hughes… - Journal of colloid and …, 2018‏ - Elsevier
The interactions between perfluoroalkyl substances (PFASs) and a phospholipid bilayer (1,
2-dimyristoyl-sn-glycero-3-phosphocholine) were investigated at the molecular level using …

Establishing a definition of polar bear (Ursus maritimus) health: a guide to research and management activities

KA Patyk, C Duncan, P Nol, C Sonne, K Laidre… - Science of the Total …, 2015‏ - Elsevier
The meaning of health for wildlife and perspectives on how to assess and measure health,
are not well characterized. For wildlife at risk, such as some polar bear (Ursus maritimus) …

A veterinary perspective on One Health in the Arctic

C Sonne, RJ Letcher, BM Jenssen… - Acta Veterinaria …, 2017‏ - Springer
Exposure to long-range transported industrial chemicals, climate change and diseases is
posing a risk to the overall health and populations of Arctic wildlife. Since local communities …

[HTML][HTML] Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently

R Lille-Langøy, JV Goldstone, M Rusten… - Toxicology and applied …, 2015‏ - Elsevier
Background Many persistent organic pollutants (POPs) accumulate readily in polar bears
because of their position as apex predators in Arctic food webs. The pregnane X receptor …

Penile density and globally used chemicals in Canadian and Greenland polar bears

C Sonne, M Dyck, FF Rigét, JEB Jensen… - Environmental …, 2015‏ - Elsevier
Industrially produced chemicals have been a major environmental concern across our entire
Globe since the onset of rapid industrial development around the early 1900. Many of the …

Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha …

H Routti, MK Berg, R Lille-Langøy, L Øygarden… - Scientific Reports, 2019‏ - nature.com
Peroxisome proliferator-activated receptor alfa (PPARA/NR1C1) is a ligand activated
nuclear receptor that is a key regulator of lipid metabolism in tissues with high fatty acid …

Human bodies as chemical sensors: a history of biomonitoring for environmental health and regulation

ANH Creager - Studies in History and Philosophy of Science Part A, 2018‏ - Elsevier
The testing of human blood and urine for signs of chemical exposure has become the “gold
standard” of environmental public health, leading to ongoing population studies in the US …