Articular cartilage (AC) is the weight-bearing tissue in diarthroses. It lacks the capacity for
self-healing once there are injuries or diseases due to its avascularity. With the development …

3D biodegradable porous scaffold plays a very important role in articular cartilage tissue
engineering. We developed hybrid structures of 3D scaffolds that combined the advantages …

A 3-D scaffold that simulates the microenvironment in vivo for regenerating cartilage is ideal.
In this study, we combined silk fibroin and decellularized cartilage extracellular matrix by …

Damage of cartilage due to traumatic or pathological conditions results in disability and
severe pain. Regenerative medicine, using tissue engineering-based constructs to enhance …

The structure of a cartilage scaffold is required to mimic native articular cartilage, which has
an oriented structure associated with its mechanical function. In this study, an oriented …

Accounts of happiness in the philosophical literature see it as either a judgment of
satisfaction with one's life or as a balance of positive over negative feelings or emotional …

A critical challenge in fabricating a load bearing tissue, such as an intervertebral disc, is to
simulate cellular and matrix alignment and anisotropy, as well as a specific biochemical …

This study investigated the hypothesis that controlled media mixing will enhance tissue
formation and increase mechanical properties of anatomically-shaped tissue engineered …

Significant oxygen gradients occur within tissue engineered cartilaginous constructs.
Although oxygen tension is an important limiting parameter in the development of new …

The fabrication of tissue‐engineered constructs of clinically relevant sizes continues to be
plagued by poor nutrient transport to the interior of the construct. Consequences of poor …