Efflux pump mediated antimicrobial resistance by staphylococci in health-related environments: challenges and the quest for inhibition
The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …
health threat worldwide due to significant morbidity and mortality resulting from their …
Health benefits, pharmacological effects, molecular mechanisms, and therapeutic potential of α-bisabolol
α-Bisabolol is one of the important monocyclic sesquiterpenes, derived naturally from
essential oils of many edible and ornamental plants. It was first obtained from Matricaria …
essential oils of many edible and ornamental plants. It was first obtained from Matricaria …
Terpenes as bacterial efflux pump inhibitors: A systematic review
KJSDO Dias, GM Miranda, JR Bessa… - Frontiers in …, 2022 - frontiersin.org
Managing antibiotic resistance is a significant challenge in modern pharmacotherapy. While
molecular analyses have identified efflux pump expression as an essential mechanism …
molecular analyses have identified efflux pump expression as an essential mechanism …
The Major Facilitator Superfamily and Antimicrobial Resistance Efflux Pumps of the ESKAPEE Pathogen Staphylococcus aureus
The ESKAPEE bacterial pathogen Staphylococcus aureus has posed a serious public
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …
Tackling multidrug-resistant Staphylococcus aureus by natural products and their analogues acting as NorA efflux pump inhibitors
G Kumar, AK Tudu - Bioorganic & Medicinal Chemistry, 2023 - Elsevier
Staphylococcus aureus (S. aureus) is a pathogen responsible for various community and
hospital-acquired infections with life-threatening complications like bacteraemia …
hospital-acquired infections with life-threatening complications like bacteraemia …
Microbial resistance: The role of efflux pump superfamilies and their respective substrates
ÍR Garcia, FA de Oliveira Garcia, PS Pereira… - Life Sciences, 2022 - Elsevier
The microorganism resistance to antibiotics has become one of the most worrying issues for
science due to the difficulties related to clinical treatment and the rapid spread of diseases …
science due to the difficulties related to clinical treatment and the rapid spread of diseases …
Inhibition of Staphylococcus aureus Efflux Pump by O‐Eugenol and Its Toxicity in Drosophila melanogaster Animal Model
NS Macêdo, Z de Sousa Silveira… - BioMed Research …, 2022 - Wiley Online Library
Background. Efflux pumps are transmembrane proteins that expel drugs out of a bacterial
cell contributing to microorganism drug resistance. Several studies addressing the use of …
cell contributing to microorganism drug resistance. Several studies addressing the use of …
Potentiate the activity of current antibiotics by naringin dihydrochalcone targeting the AdeABC efflux pump of multidrug-resistant Acinetobacter baumannii
P Verma, M Tiwari, V Tiwari - International Journal of Biological …, 2022 - Elsevier
Acinetobacter baumannii is an ESKAPE pathogen responsible for severe nosocomial
infections. Among all the mechanisms contributing to multidrug resistance, efflux pumps …
infections. Among all the mechanisms contributing to multidrug resistance, efflux pumps …
The role of essential oils in the inhibition of efflux pumps and reversion of bacterial resistance to antimicrobials
Due to the deaths from infections caused by multidrug-resistant microorganisms worldwide,
the World Health Organization considers antibiotic resistance to be a critical global public …
the World Health Organization considers antibiotic resistance to be a critical global public …
In Vitro and In Silico Inhibition of Staphylococcus aureus Efflux Pump NorA by α-Pinene and Limonene
Since the discovery of the first antibiotics, bacteria have acquired a variety of resistance
mechanisms, with efflux pump (EP) being the most prominent mechanism for intracellular …
mechanisms, with efflux pump (EP) being the most prominent mechanism for intracellular …