Pathophysiology of Post-COVID syndromes: a new perspective

GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, NN Welson - Virology Journal, 2022 - Springer
Most COVID-19 patients recovered with low mortality; however, some patients experienced
long-term symptoms described as “long-COVID” or “Post-COVID syndrome”(PCS). Patients …

Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

Interactions of SARS-CoV-2 with the blood–brain barrier

MA Erickson, EM Rhea, RC Knopp… - International Journal of …, 2021 - mdpi.com
Emerging data indicate that neurological complications occur as a consequence of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The blood–brain barrier …

CSF biomarkers in COVID-19 associated encephalopathy and encephalitis predict long-term outcome

M Guasp, G Muñoz-Sánchez… - Frontiers in …, 2022 - frontiersin.org
Patients with coronavirus disease 2019 (COVID-19) frequently develop acute
encephalopathy and encephalitis, but whether these complications are the result from viral …

The multifaceted role of neurofilament light chain protein in non-primary neurological diseases

S Abu-Rumeileh, A Abdelhak, M Foschi, L D'Anna… - Brain, 2023 - academic.oup.com
The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …

Inflammation at the crossroads of COVID-19, cognitive deficits and depression

NML e Silva, FGQ Barros-Aragão, FG De Felice… - …, 2022 - Elsevier
Acute neurological alterations have been associated with SARS-CoV-2 infection.
Additionally, it is becoming clear that coronavirus disease 2019 (COVID-19) survivors may …

Viral antigen and inflammatory biomarkers in cerebrospinal fluid in patients with COVID-19 infection and neurologic symptoms compared with control participants …

A Edén, A Grahn, D Bremell, A Aghvanyan… - JAMA network …, 2022 - jamanetwork.com
Importance Neurologic symptoms are common in COVID-19, but the central nervous system
(CNS) pathogenesis is unclear, and viral RNA is rarely detected in cerebrospinal fluid (CSF) …

SARS‐COV‐2 infection and Parkinson's disease: possible links and perspectives

HM Al‐kuraishy, AI Al‐Gareeb… - Journal of …, 2023 - Wiley Online Library
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
loss of dopaminergic neurons in the substantia nigra. The hallmarks are the presence of …

Widespread white matter oedema in subacute COVID-19 patients with neurological symptoms

A Rau, N Schroeter, G Blazhenets, A Dressing… - Brain, 2022 - academic.oup.com
While neuropathological examinations in patients who died from COVID-19 revealed
inflammatory changes in cerebral white matter, cerebral MRI frequently fails to detect …

[HTML][HTML] Therapeutic approaches to the neurologic manifestations of COVID-19

EL Graham, IJ Koralnik, EM Liotta - Neurotherapeutics, 2022 - Elsevier
As of May 2022, there have been more than 527 million infections with severe acute
respiratory disease coronavirus type 2 (SARS-CoV-2) and over 6.2 million deaths from …