Objective To determine the efficacy of psilocybin as an antidepressant compared with
placebo or non-psychoactive drugs. Design Systematic review and meta-analysis. Data …

While ketamine has been used clinically over the past decades, it has only been recently
shown to be a promising therapy for treatment-resistant depression (TRD). However …

Anhedonia is defined as a diminished ability to experience interest or pleasure, and is a
critical psychopathological dimension of major depressive disorder (MDD). The purpose of …

Background Ketamine and its enantiomer esketamine represent promising new treatments
for treatment-resistant depression (TRD). Esketamine induces acute, transient psychoactive …

Intravenous (IV) ketamine is increasingly used off-label at subanesthetic doses for its rapid
antidepressant effect, and intranasal (IN) esketamine has been recently approved in several …

Objectives The objective of this study was to investigate the effect of a horticultural therapy
program on reducing middle-aged women's depression and anxiety and improving their self …

Background News media coverage is a powerful influence on public attitude and
government action. The digitization of news media covering the current opioid epidemic has …

Background Given increasing community-based and off-label use of ketamine for psychiatric
indications, we examined current informed consent processes from a convenience sample …

About one-third of patients with depression do not achieve adequate response to current
treatment options. Although intravenous and intranasal administrations of (es) ketamine …

Treatment-resistant depression (TRD) is a problematic and prevalent public health and
societal concern. Although electroconvulsive therapy (ECT) is the gold standard TRD …