Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …

Biomaterials for tissue scaffolds are key components in modern tissue engineering and
regenerative medicine. Targeted reconstructive therapies require a proper choice of …

Engineered male and female biomimetic reproductive tissues are being developed as
autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell …

A transparent cornea is paramount for vision. Corneal opacity is one of the leading causes of
blindness. Although conventional corneal transplantation has been successful in recovering …

Diabetic male infertility and sub fertility are major complications that may implicate both
central and peripheral pathways as well as mechanisms controlling reproduction. This study …

Background Advances in three-dimensional culture technologies have led to progression in
systems used to model the gonadal microenvironment in vitro. Despite demonstrating basic …

Tissue‐derived decellularized extracellular matrices (dECM) have gradually become the
gold standard of scaffolds for tissue engineering, owing to their close mirroring of the …

Traditional therapeutic interventions aim to restore male fertile potential or preserve sperm
viability in severe cases, such as semen cryopreservation, testicular tissue, germ cell …

Bone regeneration can be possible through grafts or engineered bone replacement when
bone defects are larger than the critical size. Decellularized bone extracellular matrix (ECM) …

Bleomycin (BL) is a powerful chemotherapy drug that has devastating effects on
spermatogenic function and may make cancer survivors at risk of infertility. Protective effects …