Trimethylamine N-oxide (TMAO) is a biologically active molecule and is a putative promoter
of chronic diseases including atherosclerosis in humans. Host intestinal bacteria produce its …

Trimethylamine N-oxide (TMAO) is a small organic compound whose concentration in blood
increases after ingesting dietary l-carnitine and phosphatidylcholine. Recent clinical studies …

We report experimental and computational studies investigating the effects of three
osmolytes, trimethylamine N-oxide (TMAO), betaine, and glycine, on the hydrophobic …

Although it is widely known that trimethylamine N-oxide (TMAO), an osmolyte used by
nature, stabilizes the folded state of proteins, the underlying mechanism of action is not …

It has long been observed that trimethylamine N-oxide (TMAO) and urea demonstrate
dramatically different properties in a protein folding process. Even with the enormous …

Trimethylamine N-oxide (TMAO) is a naturally occurring protecting osmolyte that stabilizes
the folded state of proteins and also counteracts the destabilizing effect of urea on protein …

Osmolytes are small organic molecules that can modulate the stability and function of
cellular proteins by altering the chemical environment of the cell. Some of these osmolytes …

Osmolytes are essential for cellular function under ubiquitous osmotic stress.
Trimethylamine N-oxide (TMAO) is one such osmolyte that has gained remarkable attention …

Trimethylamine N-oxide (TMAO) protects organisms from the damaging effects of high
pressure. At the molecular level both TMAO and pressure perturb water structure but it is not …

We study aqueous solutions of the amphiphilic osmolyte trimethylamine-N-oxide (TMAO)
using broadband dielectric spectroscopy and femtosecond mid-infrared spectroscopy. Both …