Hyperthermia (HT) is a potent sensitiser for radiotherapy (RT) and chemotherapy (CT) and
has been proven to modulate directly or indirectly cells of the innate and adaptive immune …

Since its discovery in 1962 by Ritossa, the heat shock response has been extensively
studied by a number of investigators to understand the molecular mechanism underlying the …

Immunogenic cell death (ICD) has emerged as a key component of therapy-induced anti-
tumor immunity. Over the past few years, ICD was found to play a pivotal role in a wide …

Simple Summary This manuscript discusses the ongoing challenge of cancer as a leading
global cause of death despite advancements in therapies. It highlights the role of …

Hyperthermia is a cancer treatment where tumor tissue is heated to around 40° C.
Hyperthermia shows both cancer cell cytotoxicity and immune response stimulation via …

Purpose: Clinical trials combining hyperthermia with radiation and/or chemotherapy for
cancer treatment have resulted in improved overall survival and control of local recurrences …

The effects of hyperthermia on natural killer (NK) cell cytotoxicity against tumor cell targets
are not yet fully understood. A more complete understanding of these effects could be …

The skin plays an important role in thermoregulation. Identification of genes on the skin that
contribute to increased heat tolerance can be used to select animals with the best …

The adaptive immune response has evolved over hundreds of millions of years to have
exquisitely specific and durable mechanisms to eliminate pathogenic threats wherever they …

After many years, hyperthermia (HT) is experiencing a new resurgence as seen by the
positive results of many randomized trials all over the world. Tumour immunity similarly is …