The Martini model, a coarse‐grained force field for molecular dynamics simulations, has
been around for nearly two decades. Originally developed for lipid‐based systems by the …

The nanoparticle delivery system is one of the promising nanotechnology applications for
efficient drug delivery to the targeted site. However, the selection of lead excipient …

Peptide dendrimers are a type of branched, symmetric, and topologically well-defined
molecule that have already been used as delivery systems for nucleic acid transfection …

Utilization of nucleic acids (NAs) in nanotechnologies and nanotechnology‐related
applications is a growing field with broad application potential, ranging from biosensing up …

Biocompatible hydrophilic polyethylene glycol (PEG) is widely used in biomedical
applications, such as drug or gene delivery, tissue engineering or as an antifouling …

A novel approach to treating cancer has been revealed to be effective cancer vaccination. It
has also been demonstrated that nucleic acid therapies such as mRNA and siRNA are very …

A series of 6 small PAMAM dendrimers (G0-dendrimers) differing in the size, polarity and
flexibility has been synthesized. The toxicity has been investigated in three different human …

The glucocorticoid receptor (GR) is a nuclear receptor that controls critical biological
processes by regulating the transcription of specific genes. GR transcriptional activity is …

The simulation of large molecular systems remains a daunting challenge, which justifies the
exploration of novel methodologies to keep computers as an ideal companion tool for …

In order to describe the physical properties of large time scale biological systems, coarse-
grained models play an increasingly important role. In this paper we develop Coarse …