An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Post-traumatic stress disorder (PTSD) is a debilitating mental illness composed of a
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …

Importance Adverse life experiences have been proposed to contribute to diverse mental
health problems through an association with corticolimbic functioning. Despite compelling …

Background Traumatic experiences during childhood significantly impact the develo**
brain and contribute to the development of numerous physical and mental health problems …

Post-traumatic stress disorder (PTSD) is characterized by altered emotional and behavioral
responding following a traumatic event. In this article, we review the concepts of latent-state …

Abstract Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) is the gold standard
treatment for pediatric PTSD. Nonetheless, clinical outcomes in TF-CBT are highly variable …

BackgroundAdolescent internalizing symptoms and trauma exposure have been linked with
altered reward learning processes and decreased ventral striatal responses to rewarding …

Background Early-life assaultive violence exposure is a potent risk factor for posttraumatic
stress disorder (PTSD) and other mood and anxiety disorders. Neurocircuitry models posit …

Although experiencing child abuse (ie, physical abuse, sexual abuse, exposure to violence)
is associated with a variety of mental health difficulties, simple exposure to abuse does not …

Childhood trauma exposure is common and is associated with poor clinical outcomes in
adolescence along with mental health and sociodemographic challenges in adulthood …