[HTML][HTML] Tumor hypoxia and radiotherapy: A major driver of resistance even for novel radiotherapy modalities

C Beckers, M Pruschy, I Vetrugno - Seminars in Cancer Biology, 2024 - Elsevier
Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy.
Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic …

Stereotactic body radiotherapy for colorectal cancer liver metastases: a systematic review

F Petrelli, T Comito, S Barni, G Pancera… - Radiotherapy and …, 2018 - Elsevier
Introduction While surgery is the preferred option for isolated, operable liver metastases from
colorectal cancer (CRC), ablative techniques are endorsed for medically or technically …

[HTML][HTML] ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

E Van Cutsem, A Cervantes, R Adam, A Sobrero… - Annals of …, 2016 - Elsevier
Colorectal cancer (CRC) is one of the most common malignancies in Western countries.
Over the last 20 years, and the last decade in particular, the clinical outcome for patients with …

Stereotactic Body Radiotherapy (SBRT) for liver metastasis–clinical outcomes from the international multi-institutional RSSearch® Patient Registry

A Mahadevan, O Blanck, R Lanciano, A Peddada… - Radiation …, 2018 - Springer
Background Stereotactic body radiotherapy (SBRT) is an emerging treatment option for liver
metastases in patients unsuitable for surgery. We investigated factors associated with …

Final results of a phase II trial for stereotactic body radiation therapy for patients with inoperable liver metastases from colorectal cancer

M Scorsetti, T Comito, A Tozzi, P Navarria… - Journal of cancer …, 2015 - Springer
Purpose To evaluate the feasibility and efficacy of stereotactic body radiation therapy
(SBRT) in the treatment of colorectal liver metastases. Methods Forty-two patients with …

Is stereotactic body radiation therapy an attractive option for unresectable liver metastases? A preliminary report from a phase 2 trial

M Scorsetti, S Arcangeli, A Tozzi, T Comito… - International Journal of …, 2013 - Elsevier
PURPOSE: To evaluate the feasibility of high-dose stereotactic body radiation therapy
(SBRT) in the treatment of unresectable liver metastases. METHODS AND MATERIALS …

Radiotherapy for liver metastases: a review of evidence

M Høyer, A Swaminath, S Bydder, M Lock… - International Journal of …, 2012 - Elsevier
Over the past decade, there has been an increasing use of radiotherapy (RT) for the
treatment of liver metastases. Most often, ablative doses are delivered to focal liver …

[PDF][PDF] Stereotactic body radiotherapy for liver tumors

F Sterzing, TB Brunner, I Ernst, WW Baus… - Strahlentherapie und …, 2014 - researchgate.net
Original article breast, gastrointestinal, and urologic tu mors. Survival rates were reported to
be at 36 and 23% after 5 and 10 years. The best rates were reported for breast cancer and …

Phase II trial on SBRT for unresectable liver metastases: long-term outcome and prognostic factors of survival after 5 years of follow-up

M Scorsetti, T Comito, E Clerici, C Franzese, A Tozzi… - Radiation …, 2018 - Springer
Background The aim of this study was to evaluate long-term efficacy and survival prognostic
factors of stereotactic body radiation therapy (SBRT) for un-resectable liver metastases in …

Phase II study of proton-based stereotactic body radiation therapy for liver metastases: importance of tumor genotype

TS Hong, JY Wo, DR Borger, BY Yeap… - JNCI: Journal of the …, 2017 - academic.oup.com
Background We evaluated the efficacy and safety of risk-adapted, proton-based stereotactic
body radiation therapy (SBRT) for liver metastases from solid tumors. Methods This single …