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Neurodevelopmental disorders: from genetics to functional pathways
I Parenti, LG Rabaneda, H Schoen, G Novarino - Trends in Neurosciences, 2020 - cell.com
Neurodevelopmental disorders (NDDs) are a class of disorders affecting brain development
and function and are characterized by wide genetic and clinical variability. In this review, we …
and function and are characterized by wide genetic and clinical variability. In this review, we …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
A synaptic perspective of fragile X syndrome and autism spectrum disorders
C Bagni, RS Zukin - Neuron, 2019 - cell.com
Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …
The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …
related disorders. Several review articles have focused on aspects of post-mortem …
A selective review of the excitatory-inhibitory imbalance in schizophrenia: underlying biology, genetics, microcircuits, and symptoms
Y Liu, P Ouyang, Y Zheng, L Mi, J Zhao… - Frontiers in cell and …, 2021 - frontiersin.org
Schizophrenia is a chronic disorder characterized by specific positive and negative primary
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …
symptoms, social behavior disturbances and cognitive deficits (eg, impairment in working …
Lessons learned from studying syndromic autism spectrum disorders
Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single …
conditions, typically associated with chromosomal abnormalities or mutations in a single …
Autism as a disorder of high intelligence
BJ Crespi - Frontiers in neuroscience, 2016 - frontiersin.org
A suite of recent studies has reported positive genetic correlations between autism risk and
measures of mental ability. These findings indicate that alleles for autism overlap broadly …
measures of mental ability. These findings indicate that alleles for autism overlap broadly …
The emerging picture of autism spectrum disorder: genetics and pathology
Autism spectrum disorder (ASD) is defined by impaired social interaction and
communication accompanied by stereotyped behaviors and restricted interests. Although …
communication accompanied by stereotyped behaviors and restricted interests. Although …
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
M Richter, N Murtaza, R Scharrenberg, SH White… - Molecular …, 2019 - nature.com
Atypical brain connectivity is a major contributor to the pathophysiology of
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …
Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors
R Bhandari, JK Paliwal, A Kuhad - … food intervention and therapy for autism …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …