Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

Thiazole derivatives remains honored heterocycles in the field of medicinal chemistry. This
scaffold has been proven as a universal motif that is present in numerous pharmacologically …

Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

A series of novel indole-azolidinone hybrids has been synthesized via Knoevenagel
reaction of 5-fluoro-3-formyl-1H-indole-2-carboxylic acid methyl ester and some …

Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …

Chagas disease is a deadly and centenary neglected disease that is recently surging as a
potential global threat. Approximately 30% of infected individuals develop chronic Chagas …

The compounds from eight different thiazolidine and thiazole series were assessed as
potential antileishmanial scaffolds. They were tested for antileishmanial activity against …

Thiazolidin-4-one derivatives have a wide range of therapeutic implementations and clinical
significance for medicinal chemistry. This heterocyclic ring has been reported to possess a …

Spectroscopic, electronic and chemical properties and molecular docking simulations of
ethyl-2-(4-ethoxybenzylidene)-7-methyl-3-oxo-5-(4-benzyloxyphenyl)-2, 3-dihydro-5H-[1, 3] …