Inhibitory leukocyte immunoglobulin-like receptors (LILRBs 1–5) transduce signals via
intracellular immunoreceptor tyrosine-based inhibitory motifs that recruit phosphatases to …

Osteoporosis is a common systemic bone disease caused by the imbalance between
osteogenic activity and osteoclastic activity. Aged women are at higher risk of osteoporosis …

Haematological malignancies comprise a diverse group of life-threatening systemic
diseases, including leukaemia, lymphoma, and multiple myeloma. Currently available …

The suppression of bone formation is a hallmark of multiple myeloma. Myeloma cells inhibit
osteoblastogenesis from mesenchymal stem cells (MSCs), which can also differentiate into …

The development of three-dimensional environments to mimic the in vivo cellular response
is a problem in the building of disease models. This study aimed to synthesize and validate …

Multiple myeloma (MM) clones reside in the bone marrow (BM), which plays a role in its
survival and development. The interactions between MM and their neighboring …

The leukocyte immunoglobulin-like receptor B (LILRB) proteins, characterized by their
transmembrane nature and canonical immunoreceptor tyrosine-based inhibitory motifs …

Bone marrow mesenchymal stem cells (MSCs) may have contrasting impacts on the
progression of multiple myeloma (MM). Priming normal MSCs, by culturing them with MM …

Autologous whole cell vaccines use a patient's own tumor cells as a source of antigen to
elicit an anti-tumor immune response in vivo. Recently, the authors conducted a systematic …

The comprehension of the underlying mechanisms of the interactions within microbial
communities represents a major challenge to be faced to control their outcome. Joint efforts …