Extracellular vesicles (EVs) are known mediators of intercellular communication for both
normal and tumour cells. With the capability to transfer nucleic acids, proteins and lipids …

Brain tumours are a serious concern among both physicians and patients. The most feared
brain tumour is glioblastoma (GBM) due to its heterogeneous histology, substantial invasive …

Extracellular vesicles (EVs) act as carriers of molecular and oncogenic signatures present in
subsets of tumour cells and tumour-associated stroma, and as mediators of intercellular …

Brain tumors can be viewed as multicellular 'ecosystems' with increasingly recognized
cellular complexity and systemic impact. While the emerging diversity of malignant disease …

The coagulation system links immediate (hemostatic) and late (inflammatory, angiogenic)
tissue responses to injury, a continuum that often is subverted in cancer. Here we provide …

Research on the role of extracellular vesicles (EVs) in disease pathogenesis has been
rapidly growing over the last two decades. As EVs can mediate intercellular communication …

Glioma is the most common brain tumor. For the more aggressive form, glioblastoma,
standard treatment includes surgical resection, irradiation with adjuvant temozolomide and …

Brain vasculature is uniquely programmed to protect central nervous system tissues and
respond to their metabolic demands. These functions are subverted during the development …

Cancer-derived exosomes carry a variety of important biomarkers specific to the formation,
invasion and metastasis of tumor tissue. Dynamic monitoring of exosomes originated from …

The coagulation system constitutes an important facet of the unique vascular
microenvironment in which primary and metastatic brain tumors evolve and progress. While …