Using CellMiner 1.6 for systems pharmacology and genomic analysis of the NCI-60

WC Reinhold, M Sunshine, S Varma… - Clinical Cancer …, 2015 - aacrjournals.org
The NCI-60 cancer cell line panel provides a premier model for data integration, and
systems pharmacology being the largest publicly available database of anticancer drug …

[HTML][HTML] Amelanotic Melanoma—Biochemical and Molecular Induction Pathways

P Misiąg, K Molik, M Kisielewska, P Typek… - International Journal of …, 2024 - mdpi.com
Amelanotic melanoma (AM) is a subtype of hypomelanotic or completely amelanotic
melanoma. AM is a rare subtype of melanoma that exhibits a higher recurrence rate and …

Tissue transcriptome profiling and pathway analyses revealed novel potential biomarkers in the tumor progression of canine oral melanoma

S Pisamai, SW Edwards, CW Cheng… - Research in Veterinary …, 2023 - Elsevier
Canine oral melanoma (COM) is an aggressive oral malignancy in dogs, mostly with
metastasis. However, the understanding of total gene expression of oral melanoma (OM) at …

[HTML][HTML] The multiple roles of tyrosinase-related protein-2/L-Dopachrome tautomerase in melanoma: biomarker, therapeutic target, and molecular driver in tumor …

AL Milac, G Negroiu - Human Skin Cancers-Pathways …, 2017 - intechopen.com
Cutaneous malignant melanoma (CMM), which is ranked as the 8th most common cancers
in the US, makes 4–7% of skin cancers but it causes approximately 80% of skin cancer …

DCT protects human melanocytic cells from UVR and ROS damage and increases cell viability

SA Ainger, XL Yong, SS Wong… - Experimental …, 2014 - Wiley Online Library
Dopachrome tautomerase (DCT) is involved in the formation of the photoprotective skin
pigment eumelanin and has also been shown to have a role in response to apoptotic stimuli …

[HTML][HTML] Bg34-200 immunotherapy of advanced melanoma

V Roche, V Sandoval, Z Senders, J Lyons, C Wolford… - Cancers, 2022 - mdpi.com
Simple Summary Immunotherapy using immune checkpoint inhibitors is now the first line
standard of care for advanced melanoma but> 50% of patients still do not benefit. Using a …

Cross-talk between dopachrome tautomerase and caveolin-1 is melanoma cell phenotype-specific and potentially involved in tumor progression

IL Popa, AL Milac, LE Sima, PR Alexandru… - Journal of Biological …, 2016 - jbc.org
l-Dopachrome tautomerase (l-DCT), also called tyrosinase-related protein-2 (TRP-2), is a
melanoma antigen overexpressed in most chemo-/radiotherapeutic stress-resistant tumor …

Multicellular network analysis of melanoma heterogeneity by scRNA-seq

S Li, L Chen - American Journal of Translational Research, 2023 - pmc.ncbi.nlm.nih.gov
Objective: Melanoma neoplasia is a complicated process. Not only melanocytes are
involved, stromal cells and immune cells would also regulate cancer development …

Gene expression dataset for whole cochlea of Macaca fascicularis

H Mutai, F Miya, H Shibata, Y Yasutomi, T Tsunoda… - Scientific reports, 2018 - nature.com
Macaca fascicularis is a highly advantageous model in which to study human cochlea with
regard to both evolutionary proximity and physiological similarity of the auditory system. To …

Analysis of the difference in gene expression and mutation of glioblastoma in different age groups by using the transcriptional and exome sequencing

WZLIU Wei - Acta Anatomica Sinica, 2019 - jpxb.bjmu.edu.cn
Objective To explore the gene expression difference of glioblastoma in different age groups
through the sequencing of the transcriptome and exome. Methods Glioblastoma multiforme …