Stress-related psychopathology is on the rise, and there is a pressing need for improved
prevention strategies. Positive appraisal style, the tendency to appraise potentially …

Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

A lo largo de la vida, se experimenta estrés físico y mental de muchas formas y debido a
gran variedad de circunstancias. Sin embargo, falta mucho por conocer en relación a la …

Estrés y trastornos mentales: aspectos neurobiológicos y psicosociales SciELO - Scientific
Electronic Library Online vol.40 suppl.2 Presentación Trastorno por estrés postraumático: aspectos …

Depression is a multifactorial disorder with clinically heterogeneous features involving
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …

Epidemiologic studies indicate that children exposed to early adverse experiences are at
increased risk for the development of depression, anxiety disorders, or both. Persistent …

Cortical GABAergic dysfunction may underlie the pathophysiology of psychiatric disorders,
including schizophrenia. Here, we characterized a mouse strain in which the essential NR1 …

There is considerable evidence to suggest that adverse early-life experiences have a
profound effect on the develo** brain. Neurobiological changes that occur in response to …

Disruptions in homeostasis (ie, stress) place demands on the body that are met by the
activation of 2 systems, the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic …

Almost four decades of intensive research have sought to elucidate the neurobiological
bases of depression. Epidemiological studies have revealed that both genetic and …