Gut microbiota and hypertension: association, mechanisms and treatment

Z Yang, Q Wang, Y Liu, L Wang, Z Ge, Z Li… - Clinical and …, 2023 - Taylor & Francis
Objectives Hypertension is one of the most important risk factors for cardio-cerebral vascular
diseases, which brings a heavy economic burden to society and becomes a major public …

Cross-talk between gut microbiota and adipose tissues in obesity and related metabolic diseases

D Wu, H Wang, L **e, F Hu - Frontiers in Endocrinology, 2022 - frontiersin.org
The rapid increase of obesity and associated diseases has become a major global health
problem. Adipose tissues are critical for whole-body homeostasis. The gut microbiota has …

Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic

W Xu, J Yu, Y Yang, Z Li, Y Zhang, F Zhang… - Gut …, 2023 - Taylor & Francis
Compelling evidence has tightly linked gut microbiota with host metabolism homeostasis
and inspired novel therapeutic potentials against metabolic diseases (eg, hyperlipidemia) …

Berberine and health outcomes: An umbrella review

Z Li, Y Wang, Q Xu, J Ma, X Li, J Yan… - Phytotherapy …, 2023 - Wiley Online Library
Berberine is a plant extract widely used in clinical practice. This review aimed to summarize
and to grade the available evidence on the association between berberine consumption and …

[HTML][HTML] The berberine-enriched gut commensal Blautia producta ameliorates high-fat diet (HFD)-induced hyperlipidemia and stimulates liver LDLR expression

YN Yang, QC Wang, W Xu, J Yu, H Zhang… - Biomedicine & …, 2022 - Elsevier
Berberine (BBR) is an effective cholesterol-lowering drug. Although gut microbiota has been
implicated in the pharmacological activities of BBR, little evidence exists on the specific …

Recent advances in gut microbiota-associated natural products: structures, bioactivities, and mechanisms

H Dai, J Han, T Wang, WB Yin, Y Chen, H Liu - Natural product reports, 2023 - pubs.rsc.org
Covering: 2014 to June 2022 The gut microbiota has attracted increasing attention from
researchers due to its critical role in regulating human physiology and pathophysiology …

Microbial metabolite enhances immunotherapy efficacy by modulating T cell stemness in pan-cancer

D Jia, Q Wang, Y Qi, Y Jiang, J He, Y Lin, Y Sun, J Xu… - Cell, 2024 - cell.com
The immune checkpoint blockade (ICB) response in human cancers is closely linked to the
gut microbiota. Here, we report that the abundance of commensal Lactobacillus johnsonii is …

Intestinal microbiota by angiotensin receptor blocker therapy exerts protective effects against hypertensive damages

J Li, SY Wang, KX Yan, P Wang, J Jiao, YD Wang… - Imeta, 2024 - Wiley Online Library
Dysbiosis of the gut microbiota has been implicated in hypertension, and drug–host–
microbiome interactions have drawn considerable attention. However, the influence of …

Targeting gut microbial bile salt hydrolase (BSH) by diet supplements: new insights into dietary modulation of human health

Y Yang, C Wu - Food & Function, 2022 - pubs.rsc.org
The gut microbiome is increasingly recognized as a vital organ that participates in nutrient
acquisition, energy regulation and maintenance of human health. Targeted manipulation of …

[HTML][HTML] Potential efficacy and mechanism of eight mild-natured and bitter-flavored TCMs based on gut microbiota: a review

W Su, Y Yang, X Zhao, J Cheng, Y Li, S Wu… - Chinese Herbal …, 2024 - Elsevier
The mild-natured and bitter-flavored traditional Chinese medicines (MB-TCMs) are an
important class of TCMs that have been widely used in clinical practice and recognized as …