Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

Resveratrol induces mitochondrial biogenesis and protects against metabolic decline, but
whether SIRT1 mediates these benefits is the subject of debate. To circumvent the …

Aging has been linked to several degenerative processes that, through the accumulation of
molecular and cellular damage, can progressively lead to cell dysfunction and organ failure …

Enormous strides have recently been made in our understanding of the biology and
pathobiology of mitochondria. Many diseases have been identified as caused by …

The amyloid β peptide (Aβ) is a critical initiator that triggers the progression of Alzheimer's
Disease (AD) via accumulation and aggregation, of which the process may be caused by Aβ …

Background Sedentary behavior is emerging as an independent risk factor for chronic
disease and mortality. However, the evidence relating television (TV) viewing and other …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and highly fatal
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …

Whereas ionizing radiation (Ir) instantaneously causes the formation of water radiolysis
products that contain some reactive oxygen species (ROS), ROS are also suggested to be …

Background: Sedentary behavior (prolonged sitting or reclining characterized by low energy
expenditure) is associated with adverse cardiometabolic profiles and premature …