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[HTML][HTML] An overview of biofilm formation–combating strategies and mechanisms of action of antibiofilm agents
Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …
major health issue globally. The biofilm lifestyle provides resistance to environmental …
Quorum sensing: a prospective therapeutic target for bacterial diseases
Bacterial quorum sensing (QS) is a cell‐to‐cell communication in which specific signals are
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …
Bacterial quorum sensing: its role in virulence and possibilities for its control
ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …
information about cell density and adjust gene expression accordingly. This process …
A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation
CT O'Loughlin, LC Miller, A Siryaporn… - Proceedings of the …, 2013 - pnas.org
Quorum sensing is a chemical communication process that bacteria use to regulate
collective behaviors. Disabling quorum-sensing circuits with small molecules has been …
collective behaviors. Disabling quorum-sensing circuits with small molecules has been …
Exploiting quorum sensing to confuse bacterial pathogens
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …
is used to coordinate gene expression among local populations. Its use by bacterial …
Quorum sensing inhibitors as anti-biofilm agents
G Brackman, T Coenye - Current pharmaceutical design, 2015 - benthamdirect.com
Biofilms are microbial sessile communities characterized by cells that are attached to a
substratum or interface or to each other, are embedded in a self-produced matrix of …
substratum or interface or to each other, are embedded in a self-produced matrix of …
Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways
Numerous species of bacteria employ a mechanism of intercellular communication known
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …
Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …
Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials
KMG O'Connell, JT Hodgkinson… - Angewandte Chemie …, 2013 - Wiley Online Library
The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th
century completely revolutionized clinical practices and helped to facilitate the development …
century completely revolutionized clinical practices and helped to facilitate the development …
Agents that inhibit bacterial biofilm formation
In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …
a biofilm can also survive harsh conditions and withstand the host's immune system …