BACKGROUND Male infertility affects> 20 million men worldwide and represents a major
health concern. Although multifactorial, male infertility has a strong genetic basis which has …

Conventional photocages only respond to short wavelength light, which is a significant
obstacle to develo** efficient phototherapy in vivo. The development of photocages …

Mouse mutants that show effects on sperm head shape, the sperm tail (flagellum), and
motility were analysed in a systematic way. This was achieved by grou** mutations in the …

Sperm capacitation involves an increase in intracellular Ca2+ concentration as well as in
protein kinase A (PKA)-dependent protein tyrosine (Tyr) phosphorylation. Interestingly, in …

Synaptotagmin‐4 (SYT4) is a membrane protein that regulates membrane traffic in neurons
in a calcium‐dependent or calcium‐independent manner. In melanocytes, the intracellular …

Abstract Oligo‐astheno‐teratozoospermia (OAT) is a common cause of male infertility, and
most of idiopathic OAT patients are thought to be caused by genetic defects. Here, we …

Sex differences are well known to be determinants of development, health and disease.
Epigenetic mechanisms are also known to differ between men and women through X …

STUDY QUESTION What is the functional significance of Tex13b in male germ cell
development and differentiation? SUMMARY ANSWER Tex13b regulates male germ cell …

NR 5A1 or steroidogenic factor 1 (SF 1) is an autosomal gene, which encodes a protein that
is a member of nuclear receptor family. NR 5A1 regulates the transcription of numerous …

Reduced fertility of male mouse hybrids relative to their parents, or hybrid sterility, is
governed by the hybrid sterility 1 (Hst1) locus. Rescue experiments with transgenes carrying …