Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease
Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
disease and a cause of significant morbidity and mortality. No longer confined to endemic …
Interleukin-12: a cytokine at the interface of inflammation and immunity
G Trinchieri - Advances in immunology, 1998 - Elsevier
Publisher Summary Although interleukin-12 (IL-12) has been discovered only relatively
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
recently, a remarkable level of knowledge has been obtained for this cytokine, and many …
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
Toll-like receptors (TLRs) have emerged as a major receptor family involved in non-self
recognition. They have a vital role in triggering innate immunity and orchestrate the acquired …
recognition. They have a vital role in triggering innate immunity and orchestrate the acquired …
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection
Activation of innate immune cells by Trypanosoma cruzi-derived molecules such as GPI
anchors and DNA induces proinflammatory cytokine production and host defense …
anchors and DNA induces proinflammatory cytokine production and host defense …
Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi
ACC Frasch - Parasitology Today, 2000 - cell.com
Trypanosomes are unable to synthesize the monosaccharide sialic acid, but some African
trypanosomes and the American Trypanosoma cruzi can incorporate sialic acid derived from …
trypanosomes and the American Trypanosoma cruzi can incorporate sialic acid derived from …
Extracellular vesicles in trypanosomatids: host cell communication
Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae:
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …
A Review on the Immunological Response against Trypanosoma cruzi
Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
Infection with the protozoan parasite Trypanosoma cruzi, the agent of Chagas disease, is
characterised by a variable clinical course–from symptomless cases to severe chronic …
characterised by a variable clinical course–from symptomless cases to severe chronic …
[HTML][HTML] Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents
Intracellular protozoan parasites are potent stimulators of cell‐mediated immunity. The
induction of macrophage proinflammatory cytokines by Trypanosoma cruzi is considered to …
induction of macrophage proinflammatory cytokines by Trypanosoma cruzi is considered to …
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production
WSX-1 is a class I cytokine receptor with homology to the IL-12 receptors and is essential for
resistance to Leishmania major infection. In the present study, we demonstrated that WSX-1 …
resistance to Leishmania major infection. In the present study, we demonstrated that WSX-1 …