Accelerated spread of antibiotic resistance genes (ARGs) induced by non-antibiotic conditions: roles and mechanisms

X Shi, Y **a, W Wei, BJ Ni - Water research, 2022 - Elsevier
The global spread of antibiotic resistance genes (ARGs) has wreaked havoc with the
treatment efficiency of antibiotics and, ultimately, anti-microbial chemotherapy, and has been …

How antimicrobial resistance is linked to climate change: an overview of two intertwined global challenges

R Magnano San Lio, G Favara, A Maugeri… - International journal of …, 2023 - mdpi.com
Globally, antimicrobial resistance (AMR) and climate change (CC) are two of the top health
emergencies, and can be considered as two interlinked public health priorities. The complex …

Emergence of methicillin resistance predates the clinical use of antibiotics

J Larsen, CL Raisen, X Ba, NJ Sadgrove… - Nature, 2022 - nature.com
The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies

D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …

Antibiotic resistance: a rundown of a global crisis

B Aslam, W Wang, MI Arshad, M Khurshid… - Infection and drug …, 2018 - Taylor & Francis
The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of
antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial …

Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design

G Bahr, LJ Gonzalez, AJ Vila - Chemical reviews, 2021 - ACS Publications
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Impacts of farmland application of antibiotic-contaminated manures on the occurrence of antibiotic residues and antibiotic resistance genes in soil: a meta-analysis …

Y Zhang, D Cheng, J **e, Y Zhang, Y Wan, Y Zhang… - Chemosphere, 2022 - Elsevier
A meta-analysis of 94 published studies was conducted to explore the impacts of farmland
application of antibiotic-contaminated manures on antibiotic concentrations and ARG …

Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches

R Zhao, K Yu, J Zhang, G Zhang, J Huang, L Ma… - Water research, 2020 - Elsevier
The presence of antibiotics can exert significant selection pressure on the emergence and
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …