Development, wiring and function of dopamine neuron subtypes

O Garritsen, EY van Battum, LM Grossouw… - Nature Reviews …, 2023 - nature.com
The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

[HTML][HTML] Advancing social behavioral neuroscience by integrating ethology and comparative psychology methods through machine learning

J Bordes, L Miranda, B Müller-Myhsok… - … & Biobehavioral Reviews, 2023 - Elsevier
Social behavior is naturally occurring in vertebrate species, which holds a strong
evolutionary component and is crucial for the normal development and survival of …

The cerebellum and anxiety

PW Chin, GJ Augustine - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Although the cerebellum is traditionally known for its role in motor functions, recent evidence
points toward the additional involvement of the cerebellum in an array of non-motor …

[HTML][HTML] Hidden variables in stress neurobiology research

AL Holloway, TN Lerner - Trends in Neurosciences, 2024 - cell.com
Among the central goals of stress neurobiology research is to understand the mechanisms
by which stressors change neural circuit function to precipitate or exacerbate psychiatric …

Inflammation in the pathogenesis of depression: a disorder of neuroimmune origin

M Corrigan, AM O'Rourke, B Moran… - Neuronal …, 2023 - portlandpress.com
There are several hypotheses concerning the underlying pathophysiological mechanisms of
major depression, which centre largely around adaptive changes in neuronal transmission …

Basolateral amygdala parvalbumin and cholecystokinin-expressing GABAergic neurons modulate depressive and anxiety-like behaviors

M Asim, H Wang, A Waris, J He - Translational psychiatry, 2024 - nature.com
The basolateral amygdala (BLA) is increasingly recognized as a key regulator of depression
and anxiety-like behaviors. However, the specific contribution of individual BLA neurons to …

Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells

M Li, XK Yang, J Yang, TX Li, C Cui, X Peng, J Lei… - Neuron, 2024 - cell.com
Erasing traumatic memory during memory reconsolidation is a promising retrieval-extinction
strategy for post-traumatic stress disorder (PTSD). Here, we developed an acute social …

Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress

J Bordes, L Miranda, M Reinhardt, S Narayan… - Nature …, 2023 - nature.com
Severe stress exposure increases the risk of stress-related disorders such as major
depressive disorder (MDD). An essential characteristic of MDD is the impairment of social …

A population of Insula neurons encodes for social preference only after acute social isolation in mice

C Glangetas, A Guillaumin, E Ladevèze… - Nature …, 2024 - nature.com
The Insula functions as a multisensory relay involved in socio-emotional processing with
projections to sensory, cognitive, emotional, and motivational regions. Notably, the …

The biology of addiction

EJ Nestler - Science Signaling, 2025 - science.org
The tools of modern genetics and neurobiology have propelled a renaissance of research
that has advanced our understanding of the pathophysiology of drug addiction. We know …