The nuclear hormone receptor superfamily includes receptors for thyroid and steroid
hormones, retinoids and vitamin D, as well as different “orphan” receptors of unknown …

CTCF is an evolutionarily conserved zinc finger (ZF) phosphoprotein that binds through
combinatorial use of its 11 ZFs to∼ 50 bp target sites that have remarkable sequence …

BACKGROUND: Tissue homeostasis depends on the balance between cell proliferation and
differentiation. Thyroid hormones (THs), through binding to their nuclear receptors, can …

The transcription factor c‐Myc is a key regulator of cell proliferation, cell growth,
differentiation, and apoptosis. Deregulated c‐myc expression possesses a high …

Thyroid hormones (TH) are essential for brain development. However, information on if and
how this key endocrine factor affects adult neurogenesis is fragmentary. We thus …

Enhancer-blocking insulators are DNA elements that disrupt the communication between a
regulatory sequence, such as an enhancer or a silencer, and a promoter. Insulators …

CTCF is a transcription factor with highly versatile functions ranging from gene activation
and repression to the regulation of insulator function and imprinting. Although many of these …

The highly conserved zinc-finger protein, CTCF, is a candidate tumor suppressor protein that
binds to highly divergent DNA sequences. CTCF has been connected to multiple functions …

TRs are transcription factors that regulate cell proliferation, differentiation, and apoptosis.
They are cellular homologs of the transcriptionally inactive viral oncogene v-erb A. We …

CTCF is a widely expressed and highly conserved multi-Zn-finger (ZF) nuclear factor.
Binding to various CTCF target sites (CTSs) is mediated by combinatorial contributions of …