Ready availability, low cost and low toxicity of cobalt salts have redirected the attention of
researchers away from noble metals, such as Pd, Rh, and Ir, towards Co in the field of C–H …

Aromatic amines are ubiquitous moieties in organic molecules and their direct
functionalization is of great interest in many research areas due to their prevalence in …

Unactivated olefins usually react poorly in conventional alkenylation reactions. Their
introduction via C–H activation is limited to aromatic acids. Herein, we disclose a C–H …

Controlling positional selectivity represents one of the most important aspects in transition-
metal-catalyzed C–H bond functionalization. However, the conventional directing template …

The classic electrophilic bromination leads to ortho-and para-bromination of anilines due to
their electron-rich properties. Herein we report the development of an unprecedented Pd …

We disclose herein the development of a versatile 1, 2-diol directing template for palladium-
catalyzed remote meta-C–H functionalization of aromatic aldehydes and ketones. In situ …

Herein, we present mC–H olefination on derivatives of phenylacetic acids by tethering with a
simple nitrile-based template through palladium catalysis. Notably, the versatility of the …

Functional group metathesis has the potential to render mild reaction conditions for C–H
functionalization. Protocols for the meta-and ortho-C–H iodination of aniline derivatives via …

The palladium-catalyzed remote meta-C–H olefination of geometrically challenging
substituted cinnamates using a nitrile directing group derived from 2-cyanobenzoic acid has …

An unprecedented intramolecular remote C–H activation via sequential 1, 4-palladium
migration with an aromatic ring as a conveyor has been described. This reaction provides an …