Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential

YL **ao, Y Gong, YJ Qi, ZM Shao… - Signal Transduction and …, 2024 - nature.com
Diet, serving as a vital source of nutrients, exerts a profound influence on human health and
disease progression. Recently, dietary interventions have emerged as promising adjunctive …

The role of extracellular vesicles in circulating tumor cell-mediated distant metastasis

S Guo, J Huang, G Li, W Chen, Z Li, J Lei - Molecular Cancer, 2023 - Springer
Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

Pre-metastatic niche: formation, characteristics and therapeutic implication

Y Wang, J Jia, F Wang, Y Fang, Y Yang… - … and Targeted Therapy, 2024 - nature.com
Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer

MK Bakht, H Beltran - Nature Reviews Urology, 2025 - nature.com
Prostate-specific membrane antigen (PSMA) is an important cell-surface imaging biomarker
and therapeutic target in prostate cancer. The PSMA-targeted theranostic 177Lu-PSMA-617 …

Gut‐liver axis: Potential mechanisms of action of food‐derived extracellular vesicles

S Zhang, Q Wang, DEL Tan, V Sikka… - Journal of …, 2024 - Wiley Online Library
Food‐derived extracellular vesicles (FEVs) are nanoscale membrane vesicles obtained from
dietary materials such as breast milk, plants and probiotics. Distinct from other EVs, FEVs …

Metabolic dysfunction-associated steatotic liver disease and its link to cancer

M Kalligeros, L Henry, ZM Younossi - Metabolism, 2024 - Elsevier
Metabolic-dysfunction associated steatotic liver disease (MASLD), formerly known as
nonalcoholic fatty liver disease (NAFLD), is a growing global health concern with significant …

Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer

K Li, W Xue, Z Lu, S Wang, J Zheng, K Lu, M Li… - Journal of Experimental …, 2024 - Springer
Background Hematological metastasis has been recognized as a crucial factor contributing
to the high rates of metastasis and mortality observed in colorectal cancer (CRC). Notably …

Hypoxia preconditioning of adipose stem cell-derived exosomes loaded in gelatin methacryloyl (GelMA) promote type H angiogenesis and osteoporotic fracture repair

X Li, S Fang, S Wang, Y **e, Y **a, P Wang… - Journal of …, 2024 - Springer
The challenges posed by delayed atrophic healing and nonunion stand as formidable
obstacles in osteoporotic fracture treatment. The processes of type H angiogenesis and …

[HTML][HTML] New insights into YAP/TAZ-TEAD-mediated gene regulation and biological processes in cancer

Y Zhao, M Sheldon, Y Sun, L Ma - Cancers, 2023 - mdpi.com
Simple Summary The Hippo pathway is crucial for regulating cell growth, organ size, and
tissue regeneration. When this pathway goes awry, it can lead to uncontrolled cell growth …

Targeting neutrophils: Mechanism and advances in cancer therapy

S Yang, J Jia, F Wang, Y Wang, Y Fang… - Clinical and …, 2024 - Wiley Online Library
Background Cancer is a thorny problem which cannot be conquered by mankind at present
and recent researchers have put their focus on tumor microenviroment. Neutrophils, the …