Primary failure of eruption (PFE): a systematic review

M Hanisch, L Hanisch, J Kleinheinz, S Jung - Head & Face Medicine, 2018 - Springer
Background Primary failure of eruption (PFE) is a rare disease defined as incomplete tooth
eruption despite the presence of a clear eruption pathway. Orthodontic extrusion is not …

Mesenchymal progenitor regulation of tooth eruption: a view from PTHrP

M Nagata, N Ono, W Ono - Journal of Dental Research, 2020 - journals.sagepub.com
Tooth eruption is a unique biological process by which highly mineralized tissues emerge
into the outer world, and it occurs concomitantly with tooth root formation. These 2 processes …

Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption

A Takahashi, M Nagata, A Gupta… - Proceedings of the …, 2019 - National Acad Sciences
Formation of functional skeletal tissues requires highly organized steps of mesenchymal
progenitor cell differentiation. The dental follicle (DF) surrounding the develo** tooth …

[HTML][HTML] Primary failure of tooth eruption: Etiology and management

T Yamaguchi, K Hosomichi, T Shirota… - … Dental Science Review, 2022 - Elsevier
Primary failure of eruption (PFE) is a rare disorder defined as incomplete tooth eruption
despite the presence of a clear eruption pathway. PFE is known to be caused by rare …

A three‐dimensional analysis of primary failure of eruption in humans and mice

N Tokavanich, A Gupta, M Nagata, A Takahashi… - Oral …, 2020 - Wiley Online Library
Objectives Primary failure of eruption (PFE) is a genetic disorder exhibiting the cessation of
tooth eruption. Loss‐of‐function mutations in parathyroid hormone (PTH)/parathyroid …

KMT2C, a histone methyltransferase, is mutated in a family segregating non-syndromic primary failure of tooth eruption

AA Assiry, AM Albalawi, MS Zafar, SD Khan, A Ullah… - Scientific Reports, 2019 - nature.com
Primary failure of tooth eruption (PFE) is a rare odontogenic defect and is characterized by
failure of eruption of one or more permanent teeth. The aim of the study is to identify the …

Etiological Mechanisms and Genetic/Biological Modulation Related to PTH1R in Primary Failure of Tooth Eruption

X Li, M Wang, Z Wu, Q Sun, N Ono, M Nagata… - Calcified Tissue …, 2024 - Springer
Primary failure of eruption (PFE) is a rare disorder that is characterized by the inability of a
molar tooth/teeth to erupt to the occlusal plane or to normally react to orthodontic force. This …

Report of second case and clinical and molecular characterization of Eiken syndrome

A Moirangthem, DL Narayanan, P Jacob… - Clinical …, 2018 - Wiley Online Library
We report a boy with Eiken syndrome caused by a homozygous missense variant in
Parathyroid hormone 1 receptor (PTH1R) c. 103G> A [p.(Glu35Lys)]. Eiken syndrome is a …

Primary Failure of Dental Eruption Due to Variants Parathyroid Hormone Receptor 1: Retrospective Study and Proposal of Guidelines Treatment

A Thuaire, H Delebarre, L Marsili… - Journal of …, 2024 - journals.lww.com
Objective: Primary failure of eruption is characterized by a nonsyndromic defect in tooth
eruption in the absence of mechanical obstruction. It is correlated to rare heterozygous …

Primary Failure Eruption: Genetic Investigation, Diagnosis and Treatment: A Systematic Review

F Inchingolo, I Ferrara, F Viapiano, AM Ciocia… - Children, 2023 - mdpi.com
Aim: The aim of this systematic review is to explore the pathology, diagnosis, treatment, and
genetic basis of Primary Failure of Eruption (PFE) in the field of pediatric dentistry and …