Chemical approaches to optimize the properties of organic fluorophores for imaging and sensing

G Jiang, H Liu, H Liu, G Ke, TB Ren… - Angewandte …, 2024 - Wiley Online Library
Organic fluorophores are indispensable tools in cells, tissue and in vivo imaging, and have
enabled much progress in the wide range of biological and biomedical fields. However …

ZnO nanomaterials: Green synthesis, toxicity evaluation and new insights in biomedical applications

R Verma, S Pathak, AK Srivastava, S Prawer… - Journal of Alloys and …, 2021 - Elsevier
Nanotechnology has engraved new insight into the material sciences and zinc oxide
nanomaterials (ZnO NMs) are one of the most extensively used materials in healthcare and …

General design strategy to precisely control the emission of fluorophores via a twisted intramolecular charge transfer (TICT) process

K Hanaoka, S Iwaki, K Yagi, T Myochin… - Journal of the …, 2022 - ACS Publications
Fluorogenic probes for bioimaging have become essential tools for life science and
medicine, and the key to their development is a precise understanding of the mechanisms …

Hybrid small-molecule/protein fluorescent probes

M Minoshima, SI Reja, R Hashimoto, K Iijima… - Chemical …, 2024 - ACS Publications
Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Super-resolution microscopy for structural cell biology

S Liu, P Hoess, J Ries - Annual Review of Biophysics, 2022 - annualreviews.org
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …

Fluorescent probes for organelle-targeted bioactive species imaging

P Gao, W Pan, N Li, B Tang - Chemical science, 2019 - pubs.rsc.org
Bioactive species, including reactive oxygen species (ROS, including O2˙−, H2O2, HOCl,
1O2,˙ OH, HOBr, etc.), reactive nitrogen species (RNS, including ONOO−, NO, NO2, HNO …

Small-molecule fluorescent probes for live-cell super-resolution microscopy

L Wang, MS Frei, A Salim… - Journal of the American …, 2018 - ACS Publications
Super-resolution fluorescence microscopy is a powerful tool to visualize biomolecules and
cellular structures at the nanometer scale. Employing these techniques in living cells has …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Cellular and biophysical applications of genetic code expansion

HB Yi, S Lee, K Seo, H Kim, M Kim, HS Lee - Chemical Reviews, 2024 - ACS Publications
Despite their diverse functions, proteins are inherently constructed from a limited set of
building blocks. These compositional constraints pose significant challenges to protein …

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

DP Hoffman, G Shtengel, CS Xu, KR Campbell… - Science, 2020 - science.org
INTRODUCTION Our textbook understanding of the nanoscale organization of the cell and
its relationship to the thousands of proteins that drive cellular metabolism comes largely from …