Acetylcholine is an essential excitatory neurotransmitter in the central nervous system and
undertakes a vital role in cognitive function. Consequently, there is ample evidence to …

Alzheimer's disease (AD) is well-known as a severe neurodegeneration disease involving
complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical …

Acetylcholine is a potent excitatory neurotransmitter, crucial for cognition and the control of
alertness and arousal. Vigilance-specific recordings of the electroencephalogram (EEG) …

Late-stage neuropathological hallmarks of Alzheimer's disease (AD) are β-amyloid (βA) and
hyperphosphorylated tau peptides, aggregated into plaques and tangles, respectively …

Background The mammalian brain expresses a wide range of state-dependent network
oscillations which vary in frequency and spatial extension. Such rhythms can entrain …

Remembering to execute deferred goals (prospective memory) is a ubiquitous memory
challenge, and one that is often not successfully accomplished. Could slee** after goal …

There is growing interest in sleep research and increasing demand for screening of
circadian rhythms in genetically modified animals. This requires reliable sleep stage scoring …

With the increasing aging population, neurodegenerative disorders will become more
common in clinical practice. These disorders involve multiple pathophysiological …

Circadian rhythms in physiology and behavior exist in all living organisms, from cells to
humans. The most evident rhythms are the recurrent cycles of sleep and wake as well as …

Sleep disturbances are common in Alzheimer's disease (AD) and now assumed to
contribute to disease onset and progression. Here, we investigated whether activity …